Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Recruiting 1Completed 1

Sponsor Class

OTHER 11NIH 2INDUSTRY 2UNKNOWN 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Lymphoid 2

Conditions

Lymphoma 341Precursor Cell Lymphoblastic Leukemia-Lymphoma 264Leukemia, Lymphocytic, Chronic, B-Cell 249Lymphoma, Non-Hodgkin 227Lymphoma, Large B-Cell, Diffuse 208Lymphoma, Follicular 201Burkitt Lymphoma 183Lymphoma, Mantle-Cell 166Leukemia 148Lymphoma, B-Cell, Marginal Zone 145Hodgkin Disease 141Lymphoma, Large-Cell, Immunoblastic 124Lymphoma, T-Cell, Cutaneous 108Leukemia, Myeloid, Acute 106Multiple Myeloma 97Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 96Lymphoma, Large-Cell, Anaplastic 96Mycosis Fungoides 90Sezary Syndrome 87Waldenstrom Macroglobulinemia 84Immunoblastic Lymphadenopathy 73Neoplasms 60Myelodysplastic Syndromes 59Blast Crisis 57Intraocular Lymphoma 49Hematologic Neoplasms 46Congenital Abnormalities 45Myeloproliferative Disorders 44Dendritic Cell Sarcoma, Interdigitating 44Leukemia, Myelomonocytic, Chronic 42

Interventions

fludarabine 2Cyclophosphamide 2fludarabine phosphate 1Magnetic Resonance Imaging 1Electrocardiography 1Echocardiography 1Diphenhydramine 1Blood Component Removal 1Antiemetics 1Acetaminophen 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Philadelphia Chromosome × Lymphoid × Clear all
NCT05442515 2026-05-28

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1/2 Recruiting
130 enrolled
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Lymphoma, Lymphoma, Non-Hodgkin, Philadelphia Chromosome, Leukemia, B-Cell, Lymphoma, B-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03448393 2025-06-04

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
54 enrolled 24 charts
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Lymphoma, Lymphoma, Non-Hodgkin, Philadelphia Chromosome, Leukemia, B-Cell, Lymphoma, B-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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