Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Completed 1Active not recruiting 1

Sponsor Class

OTHER 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Lymphoid 2Other neoplasm 1

Conditions

Lymphoma 32Precursor Cell Lymphoblastic Leukemia-Lymphoma 27Leukemia 22Lymphoma, Non-Hodgkin 18Hodgkin Disease 11Leukemia, Myeloid, Acute 10Myelodysplastic Syndromes 9Leukemia, Lymphocytic, Chronic, B-Cell 9Burkitt Lymphoma 8Leukemia, Myelogenous, Chronic, BCR-ABL Positive 7Neoplasms 6Lymphoma, Large B-Cell, Diffuse 6Lymphoma, Mantle-Cell 5Lymphoma, Follicular 5Hematologic Neoplasms 5Recurrence 4Myeloproliferative Disorders 4Multiple Myeloma 4Leukemia, Biphenotypic, Acute 4Leukemia, B-Cell 4Hematologic Diseases 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Leukemia, Lymphoid 3Waldenstrom Macroglobulinemia 2Primary Myelofibrosis 2Preleukemia 2Precancerous Conditions 2Neoplasms by Histologic Type 2Lymphoproliferative Disorders 2Lymphoma, Large-Cell, Immunoblastic 2

Interventions

Cyclophosphamide 54fludarabine phosphate 48Peripheral Blood Stem Cell Transplantation 37Tacrolimus 36Mycophenolic Acid 35Whole-Body Irradiation 30Busulfan 29Antilymphocyte Serum 26Cyclosporine 23Methotrexate 21fludarabine 19Melphalan 18Filgrastim 18Radiotherapy 13Methylprednisolone 12Etoposide 12Cord Blood Stem Cell Transplantation 12thymoglobulin 11Sirolimus 11Psychiatric Rehabilitation 9Flow Cytometry 9Stem Cell Transplantation 7Granulocyte Colony-Stimulating Factor 7Therapeutics 6sargramostim 5ruxolitinib 5Specimen Handling 5Polymerase Chain Reaction 5Cytarabine 5Cyclosporins 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Primary Myelofibrosis × Mesna × Lymphoid × Clear all
NCT06001385 2026-02-05

OPTIMIZE

Center for International Blood and Marrow Transplant Research

Phase 2 Active not recruiting
313 enrolled
LymphoidMyeloidOther hematologic neoplasmOther neoplasm

Bone Marrow Diseases, Hematologic Diseases, Immune System Diseases, Immunoproliferative Disorders, Leukemia, Leukemia, Lymphoid, Leukemia, Myeloid, Lymphatic Diseases, Lymphoma, Lymphoproliferative Disorders, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

NCT02167958 2019-10-15

Nonmyeloablative Hematopoietic Cell Transplantation (HCT) for Patients With Hematologic Malignancies Using Related, HLA-Haploidentical Donors: A Pilot Trial of Peripheral Blood Stem Cells (PBSC) as the Donor Source

University of Pittsburgh

Phase 1 Completed
28 enrolled
LymphoidMyeloidOther hematologic neoplasm

Leukemia, Lymphoma, Primary Myelofibrosis

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