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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Endocrine 2Sarcoma 1Other hematologic neoplasm 1Lymphoid 1CNS 1

Conditions

Lymphoma 341Precursor Cell Lymphoblastic Leukemia-Lymphoma 264Leukemia, Lymphocytic, Chronic, B-Cell 249Lymphoma, Non-Hodgkin 227Lymphoma, Large B-Cell, Diffuse 208Lymphoma, Follicular 201Burkitt Lymphoma 183Lymphoma, Mantle-Cell 166Leukemia 148Lymphoma, B-Cell, Marginal Zone 145Hodgkin Disease 141Lymphoma, Large-Cell, Immunoblastic 124Lymphoma, T-Cell, Cutaneous 108Leukemia, Myeloid, Acute 106Multiple Myeloma 97Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 96Lymphoma, Large-Cell, Anaplastic 96Mycosis Fungoides 90Sezary Syndrome 87Waldenstrom Macroglobulinemia 84Immunoblastic Lymphadenopathy 73Neoplasms 60Myelodysplastic Syndromes 59Blast Crisis 57Intraocular Lymphoma 49Hematologic Neoplasms 46Congenital Abnormalities 45Myeloproliferative Disorders 44Dendritic Cell Sarcoma, Interdigitating 44Leukemia, Myelomonocytic, Chronic 42

Interventions

Dexamethasone 1Calcium Dobesilate 12,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
NIH × Prolactinoma × Lymphoid × Clear all
NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
129 enrolled
CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

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