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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Endocrine 2Sarcoma 1Other hematologic neoplasm 1Lymphoid 1CNS 1

Conditions

Lymphoma 370Lymphoma, Non-Hodgkin 348Leukemia, Lymphocytic, Chronic, B-Cell 322Precursor Cell Lymphoblastic Leukemia-Lymphoma 291Lymphoma, Large B-Cell, Diffuse 244Lymphoma, Follicular 236Leukemia 198Hodgkin Disease 171Lymphoma, Mantle-Cell 164Leukemia, Myeloid, Acute 160Multiple Myeloma 134Myelodysplastic Syndromes 130Recurrence 125Burkitt Lymphoma 123Lymphoma, B-Cell, Marginal Zone 120Lymphoma, T-Cell, Cutaneous 92Neoplasms 82Mycosis Fungoides 82Lymphoma, B-Cell 82Waldenstrom Macroglobulinemia 74Leukemia, Myelogenous, Chronic, BCR-ABL Positive 70Sezary Syndrome 67Lymphoma, Large-Cell, Immunoblastic 65Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 57Lymphoma, Large-Cell, Anaplastic 54Neoplasms, Plasma Cell 52Myeloproliferative Disorders 52Primary Myelofibrosis 46Hematologic Neoplasms 44Blast Crisis 43

Interventions

Dexamethasone 1Calcium Dobesilate 12,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Terminated × Prolactinoma × Lymphoid × Clear all
NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
129 enrolled
CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

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