Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Terminated 1Recruiting 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 4Head & Neck 3Dermatologic 3Myeloid 2Lymphoid 2CNS 2Breast 2Other hematologic neoplasm 1Genitourinary 1Gastrointestinal 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 226Lymphoma 221Lymphoma, Non-Hodgkin 194Leukemia, Lymphocytic, Chronic, B-Cell 175Lymphoma, Large B-Cell, Diffuse 170Lymphoma, Follicular 164Lymphoma, B-Cell 108Lymphoma, Mantle-Cell 102Hodgkin Disease 99Recurrence 94Leukemia, Myeloid, Acute 94Multiple Myeloma 89Burkitt Lymphoma 86Leukemia 76Neoplasms 66Hematologic Neoplasms 58Lymphoma, B-Cell, Marginal Zone 56Myelodysplastic Syndromes 52Waldenstrom Macroglobulinemia 42Lymphoma, T-Cell 42Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 37Lymphoma, T-Cell, Peripheral 35Lymphoma, T-Cell, Cutaneous 31Leukemia, Biphenotypic, Acute 28Leukemia, Myelogenous, Chronic, BCR-ABL Positive 27Leukemia, B-Cell 27Mycosis Fungoides 25Lymphoma, Large-Cell, Anaplastic 25Sarcoma 24Lymphoproliferative Disorders 20

Interventions

temsirolimus 1Valproic Acid 1Sirolimus 1Immunoglobulin G 1Disulfides 1Cetuximab 1Bevacizumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Soft Tissue Neoplasms × Lymphoid × 90 days × Clear all
NCT01552434 2026-05-15

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

M.D. Anderson Cancer Center

Phase 1 Terminated
154 enrolled
BreastCNSGenitourinaryHead & NeckLymphoidMyeloidSarcoma

Breast Neoplasms, Carcinoma, Transitional Cell, Endocrine Gland Neoplasms, Castleman Disease, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms, Pharyngeal Neoplasms, Recurrence, Sarcoma, Soft Tissue Neoplasms, Thyroid Neoplasms, Urologic Neoplasms, Neurofibromatosis 2, Lymphangioleiomyomatosis, Neoplasms, Mesothelial, Erdheim-Chester Disease

NCT04996875 2026-05-05

APEX

Cogent Biosciences, Inc.

Phase 2 Recruiting
140 enrolled
LymphoidMyeloidOther hematologic neoplasm

Hematologic Diseases, Hypersensitivity, Immune Complex Diseases, Immune System Diseases, Leukemia, Leukemia, Mast-Cell, Leukemia, Myeloid, Mastocytosis, Myeloproliferative Disorders, Neoplasms, Neoplasms by Site, Neoplasms, Connective Tissue, Skin Diseases, Soft Tissue Neoplasms, Urticaria Pigmentosa, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Mastocytosis, Systemic

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