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Phase

Phase 1 1

Status

Active not recruiting 5Recruiting 2Terminated 1Not yet recruiting 1Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Dermatologic 37Gastrointestinal 19Thoracic 11Tumor-Agnostic 9Other hematologic neoplasm 6Head & Neck 5CNS 5Breast 5Sarcoma 3Plasma cell 3Other solid neoplasm 3Endocrine 3Myeloid 2Gynecologic 2Lymphoid 1

Conditions

Rhabdoid Tumor 1Recurrence 1Pyloric Stenosis, Hypertrophic 1Pinealoma 1Oligodendroglioma 1Neuroectodermal Tumors, Primitive 1Neoplasms, Neuroepithelial 1Neoplasms, Germ Cell and Embryonal 1Neoplasms 1Microphthalmia, Isolated, with Coloboma 5 1Meningioma 1Medulloblastoma 1Lymphoma, Follicular 1Glioma 1Glioblastoma 1Ependymoma 1Choroid Plexus Carcinoma 1Central Nervous System Neoplasms 1Brain Neoplasms 1Astrocytoma 1

Interventions

Rituximab 702Cyclophosphamide 645Vincristine 353Doxorubicin 309Etoposide 305Cytarabine 271Filgrastim 250Prednisone 249Methotrexate 241fludarabine phosphate 231Dexamethasone 209fludarabine 184Peripheral Blood Stem Cell Transplantation 166Radiotherapy 161Granulocyte Colony-Stimulating Factor 145Lenalidomide 144Bendamustine Hydrochloride 142Bortezomib 127Melphalan 126ibrutinib 111Busulfan 111Mycophenolic Acid 108Whole-Body Irradiation 107Tacrolimus 96Cyclosporine 87Gemcitabine 82Ifosfamide 80Calcium Dobesilate 80Alemtuzumab 80Leucovorin 78

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × trametinib × Lymphoid × Clear all
NCT03434262 2024-05-31

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

St. Jude Children's Research Hospital

Phase 1 Completed
68 enrolled
CNSLymphoid

Choroid Plexus Carcinoma, Microphthalmia, Isolated, with Coloboma 5, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Lymphoma, Follicular, Medulloblastoma, Meningioma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pinealoma, Recurrence, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

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