Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Completed 2

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Classical hematology 2Lymphoid 1

Conditions

Myelodysplastic Syndromes 8Leukemia, Myelomonocytic, Chronic 7Leukemia 7Leukemia, Myeloid, Acute 6Anemia, Refractory, with Excess of Blasts 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Polycythemia Vera 4Blast Crisis 4Thrombocythemia, Essential 3Primary Myelofibrosis 3Myeloproliferative Disorders 3Myelodysplastic-Myeloproliferative Diseases 2Leukemia, Promyelocytic, Acute 2Leukemia, Myelomonocytic, Acute 2Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 2Leukemia, Monocytic, Acute 2Leukemia, Megakaryoblastic, Acute 2Leukemia, Erythroblastic, Acute 2Anemia, Refractory 2Waldenstrom Macroglobulinemia 1Thrombocytopenia 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precancerous Conditions 1Neoplasms, Plasma Cell 1Multiple Myeloma 1Monoclonal Gammopathy of Undetermined Significance 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1Lymphoma, Large-Cell, Immunoblastic 1Lymphoma, Large-Cell, Anaplastic 1

Interventions

Cyclophosphamide 27Cyclosporine 22fludarabine phosphate 21Busulfan 19Peripheral Blood Stem Cell Transplantation 16Antilymphocyte Serum 16Radiotherapy 15Mycophenolic Acid 15Cord Blood Stem Cell Transplantation 15Whole-Body Irradiation 13Methotrexate 11Methylprednisolone 10Filgrastim 9Cytarabine 7Tacrolimus 6Melphalan 6Etoposide 6sargramostim 4fludarabine 4Thiotepa 4Decitabine 4Azacitidine 4Granulocyte Colony-Stimulating Factor 3Cyclosporins 3Arsenic Trioxide 3merphos 2Vorinostat 2Topotecan 24-phenylbutyric acid 2vatalanib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Anemia, Refractory × Topotecan × Myeloid × Clear all
NCT00003675 2016-07-20

Topotecan in Treating Patients With Myelodysplastic Syndrome

Alliance for Clinical Trials in Oncology

Phase 2 Completed
100 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT00003619 2013-06-26

Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia

National Cancer Institute (NCI)

Phase 1/2 Completed
Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Blast Crisis, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocytopenia, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

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