Announcements Trials
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Phase

Phase 4 1Phase 1 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 106Sarcoma 13Lymphoid 8Gastrointestinal 6Thoracic 4Genitourinary 4Gynecologic 3Dermatologic 3Myeloid 2Head & Neck 2Other hematologic neoplasm 1Endocrine 1Classical hematology 1Breast 1

Conditions

Myelodysplastic Syndromes 355Leukemia, Myeloid, Acute 297Myeloproliferative Disorders 155Leukemia, Myelogenous, Chronic, BCR-ABL Positive 139Precursor Cell Lymphoblastic Leukemia-Lymphoma 115Primary Myelofibrosis 101Leukemia, Myelomonocytic, Chronic 88Lymphoma, Non-Hodgkin 76Leukemia 69Polycythemia Vera 61Multiple Myeloma 55Hodgkin Disease 50Hematologic Neoplasms 48Leukemia, Lymphocytic, Chronic, B-Cell 43Lymphoma 40Leukemia, Biphenotypic, Acute 40Thrombocythemia, Essential 39Myelodysplastic-Myeloproliferative Diseases 31Neoplasms 29Leukemia, Myeloid, Chronic-Phase 28Anemia, Refractory, with Excess of Blasts 24Recurrence 22Anemia, Aplastic 21Lymphoma, Mantle-Cell 20Lymphoma, Follicular 20Hematologic Diseases 20Burkitt Lymphoma 20Blastic Plasmacytoid Dendritic Cell Neoplasm 20Blast Crisis 20Histiocytosis, Langerhans-Cell 18

Interventions

trametinib 1dabrafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Astrocytoma × Myeloid × 1 year × Clear all
NCT03975829 2026-06-02

Pediatric Long-Term Follow-up and Rollover Study

Novartis

Phase 4 Recruiting
165 enrolled
CNSMyeloid

Astrocytoma, Ganglioneuroma, Glioblastoma, Glioma, Histiocytosis, Langerhans-Cell, Neuroblastoma, Neurofibromatosis 1, Oligodendroglioma, Ganglioglioma, Neurocytoma, Neurofibroma, Plexiform

NCT02381886 2026-04-13

A Study of IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations

Novartis

Phase 1 Active not recruiting
166 enrolled
CNSGastrointestinalMyeloidOther hematologic neoplasm

Astrocytoma, Glioblastoma, Glioma, Leukemia, Myelodysplastic Syndromes, Oligodendroglioma, Leukemia, Myeloid, Acute, Cholangiocarcinoma

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