Announcements Trials
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Phase

Phase 4 1Phase 1 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 53Sarcoma 5Lymphoid 4Myeloid 2Gastrointestinal 2Thoracic 1Other hematologic neoplasm 1Gynecologic 1Genitourinary 1Breast 1

Conditions

Myelodysplastic Syndromes 159Leukemia, Myeloid, Acute 141Leukemia, Myelogenous, Chronic, BCR-ABL Positive 67Myeloproliferative Disorders 64Precursor Cell Lymphoblastic Leukemia-Lymphoma 52Primary Myelofibrosis 47Leukemia, Myelomonocytic, Chronic 40Lymphoma, Non-Hodgkin 36Leukemia 26Polycythemia Vera 23Hodgkin Disease 23Myelodysplastic-Myeloproliferative Diseases 21Multiple Myeloma 20Thrombocythemia, Essential 19Hematologic Neoplasms 19Leukemia, Lymphocytic, Chronic, B-Cell 18Neoplasms 17Leukemia, Biphenotypic, Acute 15Anemia, Refractory, with Excess of Blasts 14Sarcoma 13Histiocytosis, Langerhans-Cell 13Glioma 13Neuroblastoma 12Hematologic Diseases 12Wilms Tumor 11Rhabdoid Tumor 11Recurrence 11Osteosarcoma 11Neuroectodermal Tumors, Primitive, Peripheral 11Medulloblastoma 11

Interventions

trametinib 1dabrafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Astrocytoma × Myeloid × 90 days × Clear all
NCT03975829 2026-06-02

Pediatric Long-Term Follow-up and Rollover Study

Novartis

Phase 4 Recruiting
165 enrolled
CNSMyeloid

Astrocytoma, Ganglioneuroma, Glioblastoma, Glioma, Histiocytosis, Langerhans-Cell, Neuroblastoma, Neurofibromatosis 1, Oligodendroglioma, Ganglioglioma, Neurocytoma, Neurofibroma, Plexiform

NCT02381886 2026-04-13

A Study of IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations

Novartis

Phase 1 Active not recruiting
166 enrolled
CNSGastrointestinalMyeloidOther hematologic neoplasm

Astrocytoma, Glioblastoma, Glioma, Leukemia, Myelodysplastic Syndromes, Oligodendroglioma, Leukemia, Myeloid, Acute, Cholangiocarcinoma

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