Announcements Trials
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Phase

Phase 1 1

Status

Suspended 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Gastrointestinal 13Gynecologic 7Dermatologic 6Thoracic 5Sarcoma 5Head & Neck 4Genitourinary 4Breast 3Plasma cell 2Other solid neoplasm 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1CNS 1

Conditions

Myelodysplastic Syndromes 211Leukemia, Myeloid, Acute 181Precursor Cell Lymphoblastic Leukemia-Lymphoma 162Leukemia 125Lymphoma, Non-Hodgkin 112Hodgkin Disease 102Leukemia, Lymphocytic, Chronic, B-Cell 99Multiple Myeloma 97Leukemia, Myelogenous, Chronic, BCR-ABL Positive 91Lymphoma 88Myeloproliferative Disorders 87Lymphoma, Follicular 72Leukemia, Myelomonocytic, Chronic 72Leukemia, Myeloid, Chronic-Phase 71Lymphoma, Mantle-Cell 70Burkitt Lymphoma 67Leukemia, Myeloid, Accelerated Phase 65Primary Myelofibrosis 62Lymphoma, B-Cell, Marginal Zone 61Lymphoma, Large B-Cell, Diffuse 60Blast Crisis 53Anemia, Refractory, with Excess of Blasts 51Lymphoma, Large-Cell, Immunoblastic 50Congenital Abnormalities 50Neoplasms, Plasma Cell 47Myelodysplastic-Myeloproliferative Diseases 45Dendritic Cell Sarcoma, Interdigitating 41Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 38Graft vs Host Disease 38Leukemia, Biphenotypic, Acute 37

Interventions

vactosertib 1fludarabine phosphate 1aldesleukin 1Standard of Care 1Quality of Life 1Practice Guidelines as Topic 1Patient Reported Outcome Measures 1Palliative Care 1Molecular Diagnostic Techniques 1Interleukin-2 1Immunotherapy 1IL32 protein, human 1Fentanyl 1Drug Therapy 1Cyclophosphamide 1Biological Therapy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Esophageal Neoplasms × Cyclophosphamide × Myeloid × Clear all
NCT05400122 2025-11-12

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

Case Comprehensive Cancer Center

Phase 1 Suspended
12 enrolled
GastrointestinalLymphoidMyeloidOther hematologic neoplasmPlasma cell

Esophageal Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasm Metastasis, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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