Announcements Trials
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Phase

Phase 1 1

Status

Suspended 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Gastrointestinal 5Thoracic 1Plasma cell 1Other solid neoplasm 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1Head & Neck 1Gynecologic 1Genitourinary 1Dermatologic 1Breast 1

Conditions

Myelodysplastic Syndromes 10Leukemia, Myeloid, Acute 10Leukemia, Myelogenous, Chronic, BCR-ABL Positive 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Lymphoma, Non-Hodgkin 4Leukemia 4Hematologic Neoplasms 4Myeloproliferative Disorders 2Leukemia, Myelomonocytic, Juvenile 2Hodgkin Disease 2Congenital Abnormalities 2Thrombocythemia, Essential 1Stomach Neoplasms 1Sarcoma, Myeloid 1Rectal Neoplasms 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Polycythemia Vera 1Neoplasm Metastasis 1Multiple Myeloma 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1Leukemia, Myeloid 1Leukemia, Lymphocytic, Chronic, B-Cell 1Graft vs Host Disease 1Esophageal Neoplasms 1Colorectal Neoplasms 1Blast Crisis 1Anemia, Refractory, with Excess of Blasts 1

Interventions

vactosertib 1fludarabine phosphate 1aldesleukin 1Standard of Care 1Quality of Life 1Practice Guidelines as Topic 1Patient Reported Outcome Measures 1Palliative Care 1Molecular Diagnostic Techniques 1Interleukin-2 1Immunotherapy 1IL32 protein, human 1Fentanyl 1Drug Therapy 1Cyclophosphamide 1Biological Therapy 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Esophageal Neoplasms × Interleukin-2 × Myeloid × Clear all
NCT05400122 2025-11-12

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

Case Comprehensive Cancer Center

Phase 1 Suspended
12 enrolled
GastrointestinalLymphoidMyeloidOther hematologic neoplasmPlasma cell

Esophageal Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasm Metastasis, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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