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Phase

Phase 3 1Phase 2 1Phase 1/2 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Plasma cell 3Lymphoid 3Sarcoma 1Other hematologic neoplasm 1Myeloid 1

Conditions

Myelodysplastic Syndromes 212Leukemia, Myeloid, Acute 178Leukemia 89Precursor Cell Lymphoblastic Leukemia-Lymphoma 86Leukemia, Myelogenous, Chronic, BCR-ABL Positive 81Myeloproliferative Disorders 62Leukemia, Myelomonocytic, Chronic 61Lymphoma, Non-Hodgkin 48Multiple Myeloma 43Primary Myelofibrosis 41Hodgkin Disease 37Lymphoma 36Blast Crisis 32Leukemia, Lymphocytic, Chronic, B-Cell 29Hematologic Neoplasms 29Polycythemia Vera 26Leukemia, Myeloid, Chronic-Phase 26Leukemia, Myeloid, Accelerated Phase 26Lymphoma, Mantle-Cell 24Thrombocythemia, Essential 23Lymphoma, Follicular 21Lymphoma, Large B-Cell, Diffuse 20Burkitt Lymphoma 20Anemia, Refractory, with Excess of Blasts 20Myelodysplastic-Myeloproliferative Diseases 19Recurrence 18Congenital Abnormalities 18Neoplasms, Plasma Cell 16Lymphoma, B-Cell, Marginal Zone 16Lymphoma, Large-Cell, Immunoblastic 15

Interventions

sonidegib 1ruxolitinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Hemorrhagic Disorders × Myeloid × Clear all
NCT01787552 2020-04-15

A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MF

Novartis

Phase 1/2 Completed
50 enrolled 23 charts
Myeloid

Blood Coagulation Disorders, Blood Platelet Disorders, Bone Marrow Diseases, Hematologic Diseases, Hemorrhagic Disorders, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Thrombocytosis, Primary Myelofibrosis

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