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Phase

Phase 2 1Phase 1/2 1

Status

Suspended 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 5Gastrointestinal 5Breast 5Thoracic 3Gynecologic 3Other hematologic neoplasm 1Myeloid 1Genitourinary 1CNS 1

Conditions

Myelodysplastic Syndromes 212Leukemia, Myeloid, Acute 178Leukemia 89Precursor Cell Lymphoblastic Leukemia-Lymphoma 86Leukemia, Myelogenous, Chronic, BCR-ABL Positive 81Myeloproliferative Disorders 62Leukemia, Myelomonocytic, Chronic 61Lymphoma, Non-Hodgkin 48Multiple Myeloma 43Primary Myelofibrosis 41Hodgkin Disease 37Lymphoma 36Blast Crisis 32Leukemia, Lymphocytic, Chronic, B-Cell 29Hematologic Neoplasms 29Polycythemia Vera 26Leukemia, Myeloid, Chronic-Phase 26Leukemia, Myeloid, Accelerated Phase 26Lymphoma, Mantle-Cell 24Thrombocythemia, Essential 23Lymphoma, Follicular 21Lymphoma, Large B-Cell, Diffuse 20Burkitt Lymphoma 20Anemia, Refractory, with Excess of Blasts 20Myelodysplastic-Myeloproliferative Diseases 19Recurrence 18Congenital Abnormalities 18Neoplasms, Plasma Cell 16Lymphoma, B-Cell, Marginal Zone 16Lymphoma, Large-Cell, Immunoblastic 15

Interventions

venetoclax 1CA-4948 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Hereditary Sensory and Autonomic Neuropathies × Myeloid × Clear all
NCT04278768 2026-03-19

Dose Escalation/ Expansion Study of CA-4948 as Monotherapy in Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Curis, Inc.

Phase 1/2 Suspended
366 enrolled
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Hereditary Sensory and Autonomic Neuropathies, Recurrence, Leukemia, Myeloid, Acute

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