Announcements Trials
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Phase

Phase 1 2

Status

Terminated 1Completed 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Lymphoid 3Other hematologic neoplasm 2Myeloid 2Classical hematology 1

Conditions

Myeloproliferative Disorders 6Primary Myelofibrosis 4Myelodysplastic Syndromes 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Lymphoma, Non-Hodgkin 2Leukemia, Myelomonocytic, Chronic 2Leukemia, Myeloid, Acute 2Hodgkin Disease 2Thrombocytosis 1Polycythemia Vera 1Multiple Myeloma 1Lymphoma, Mantle-Cell 1Leukemia, Prolymphocytic, T-Cell 1Leukemia, Plasma Cell 1Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1Leukemia, Lymphocytic, Chronic, B-Cell 1Leukemia 1Hematologic Neoplasms 1Graft vs Host Disease 1Anemia, Refractory, with Excess of Blasts 1

Interventions

Cyclophosphamide 102fludarabine phosphate 94Mycophenolic Acid 81Tacrolimus 70Whole-Body Irradiation 65Peripheral Blood Stem Cell Transplantation 65fludarabine 49Busulfan 49Cyclosporine 48Antilymphocyte Serum 44Melphalan 39Filgrastim 37Methotrexate 32Radiotherapy 25Granulocyte Colony-Stimulating Factor 22Cord Blood Stem Cell Transplantation 20Sirolimus 19Rituximab 19thymoglobulin 18Stem Cell Transplantation 18Methylprednisolone 16Alemtuzumab 16Thiotepa 13sargramostim 11Cytarabine 11Cyclosporins 11Clofarabine 11Therapeutics 10Flow Cytometry 10Etoposide 10

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Hodgkin Disease × itacitinib × Myeloid × Clear all
NCT03320642 2025-10-21

GRAVITAS-119: Itacitinib in Combination With Calcineurin Inhibitor-Based Interventions for the Prophylaxis of Graft-Versus Host Disease

Incyte Corporation

Phase 1 Terminated
84 enrolled
Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Graft vs Host Disease, Hodgkin Disease, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Hematologic Neoplasms, Lymphoma, Mantle-Cell

NCT03755414 2025-04-06

Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Washington University School of Medicine

Phase 1 Completed
55 enrolled 11 charts
LymphoidMyeloidOther hematologic neoplasm

Hodgkin Disease, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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