Announcements Trials
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Phase

Phase 1 2Phase 1/2 1

Status

Completed 2Terminated 1

Sponsor Class

OTHER 15NIH 3INDUSTRY 3NETWORK 2

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 29Lymphoid 23Myeloid 3Plasma cell 2Sarcoma 1Classical hematology 1

Conditions

Myelodysplastic Syndromes 323Leukemia, Myeloid, Acute 276Leukemia, Myelogenous, Chronic, BCR-ABL Positive 244Leukemia 116Myeloproliferative Disorders 106Primary Myelofibrosis 100Precursor Cell Lymphoblastic Leukemia-Lymphoma 100Leukemia, Myelomonocytic, Chronic 78Polycythemia Vera 74Hematologic Neoplasms 67Multiple Myeloma 50Neoplasms 41Lymphoma, Non-Hodgkin 40Thrombocythemia, Essential 39Hematologic Diseases 38Leukemia, Lymphocytic, Chronic, B-Cell 37Recurrence 35Lymphoma 32Leukemia, Myeloid, Chronic-Phase 31Mastocytosis, Systemic 26Bone Marrow Diseases 25Leukemia, Myeloid 23Blast Crisis 23Anemia, Refractory, with Excess of Blasts 23Hodgkin Disease 21Bronchiolitis Obliterans Syndrome 16Mastocytosis 15Philadelphia Chromosome 14Leukemia, Mast-Cell 13Graft vs Host Disease 13

Interventions

tozasertib 12-(2-oxo-2-((3,7,11-trimethyl-2,6,10-dodecatrienyl)oxy)aminoethyl)phosphonic acid, (2,2-dimethyl-1-oxopropoxy)methyl ester sodium 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
INDUSTRY × Leukemia, Lymphoid × Myeloid × Clear all
NCT00111683 2015-08-25

MK0457 in Patients With Leukemia (0457-003)

Merck Sharp & Dohme LLC

Phase 1 Completed
28 enrolled
MyeloidOther hematologic neoplasm

Leukemia, Lymphoid, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT00464113 2015-08-21

Study of XL228 in Subjects With Chronic Myeloid Leukemia or Philadelphia-Chromosome-Positive Acute Lymphocytic Leukemia

Exelixis

Phase 1 Terminated
49 enrolled
LymphoidMyeloidOther hematologic neoplasm

Leukemia, Lymphoid, Leukemia, Myeloid, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00034684 2015-06-17

Study of Farnesyl Protein Transferase Inhibitor (FPTI) in Patients With Leukemia (Study P00701)

Merck Sharp & Dohme LLC

Phase 1/2 Completed
132 enrolled
MyeloidOther hematologic neoplasm

Blast Crisis, Leukemia, Leukemia, Lymphoid, Leukemia, Myeloid, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

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