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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Gastrointestinal 37Lymphoid 5Genitourinary 5Thoracic 1Plasma cell 1Other hematologic neoplasm 1NET 1Myeloid 1Endocrine 1

Conditions

Myelodysplastic Syndromes 750Leukemia, Myeloid, Acute 635Leukemia 476Leukemia, Myelogenous, Chronic, BCR-ABL Positive 470Precursor Cell Lymphoblastic Leukemia-Lymphoma 409Myeloproliferative Disorders 339Lymphoma, Non-Hodgkin 271Leukemia, Myelomonocytic, Chronic 270Leukemia, Lymphocytic, Chronic, B-Cell 264Multiple Myeloma 259Hodgkin Disease 249Primary Myelofibrosis 230Leukemia, Myeloid, Chronic-Phase 217Lymphoma 203Blast Crisis 195Leukemia, Myeloid, Accelerated Phase 182Lymphoma, Mantle-Cell 168Lymphoma, Follicular 168Burkitt Lymphoma 166Lymphoma, Large B-Cell, Diffuse 162Lymphoma, B-Cell, Marginal Zone 151Congenital Abnormalities 148Polycythemia Vera 144Lymphoma, Large-Cell, Immunoblastic 141Anemia, Refractory, with Excess of Blasts 131Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 128Myelodysplastic-Myeloproliferative Diseases 126Neoplasms, Plasma Cell 117Thrombocythemia, Essential 114Lymphoma, T-Cell, Cutaneous 99

Interventions

pevonedistat 1Azacitidine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × Liver Diseases × Myeloid × Clear all
NCT03814005 2024-09-05

A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Takeda

Phase 1 Completed
17 enrolled 33 charts
MyeloidOther hematologic neoplasm

Liver Diseases, Myelodysplastic Syndromes, Neoplasms, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Renal Insufficiency

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