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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Tumor-Agnostic 1Other hematologic neoplasm 1Myeloid 1

Conditions

Myelodysplastic Syndromes 9Leukemia, Myeloid, Acute 8Leukemia, Myelomonocytic, Chronic 4Thrombocytosis 1Thrombocythemia, Essential 1Renal Insufficiency 1Primary Myelofibrosis 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Polycythemia Vera 1Neoplasms 1Neoplasm, Residual 1Myeloproliferative Disorders 1Liver Diseases 1Leukemia, Neutrophilic, Chronic 1Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1Hypereosinophilic Syndrome 1

Interventions

Cyclophosphamide 9ruxolitinib 7Azacitidine 7fludarabine phosphate 6Whole-Body Irradiation 6Peripheral Blood Stem Cell Transplantation 6Mycophenolic Acid 6navitoclax 5fludarabine 5Therapeutics 5Busulfan 5ponatinib 4Melphalan 4Tacrolimus 3Stem Cell Transplantation 3Patient Reported Outcome Measures 3Mesna 3Immunoenzyme Techniques 3Flow Cytometry 3Cyclosporine 3Clofarabine 3Antilymphocyte Serum 3vosaroxin 2trametinib 2liposomal amphotericin B 2dabrafenib 2Watchful Waiting 2Transplantation 2Sirolimus 2Psychiatric Rehabilitation 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Neoplasms × pevonedistat × Myeloid × Clear all
NCT03814005 2024-09-05

A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Takeda

Phase 1 Completed
17 enrolled 33 charts
MyeloidOther hematologic neoplasm

Liver Diseases, Myelodysplastic Syndromes, Neoplasms, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Renal Insufficiency

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