Announcements Trials
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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 4Myeloid 1

Conditions

Myelodysplastic Syndromes 11Leukemia, Myelogenous, Chronic, BCR-ABL Positive 10Leukemia, Myeloid, Acute 8Recurrence 4Hematologic Neoplasms 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Philadelphia Chromosome 2Myeloproliferative Disorders 2Mastocytosis, Systemic 2Leukemia, Mast-Cell 2Leukemia 2Hematologic Diseases 2Bronchiolitis Obliterans Syndrome 2Bone Marrow Diseases 2Translocation, Genetic 1Pathologic Processes 1Neurofibroma, Plexiform 1Neuroblastoma 1Neoplastic Processes 1Neoplasms by Histologic Type 1Neoplasms 1Lymphoma 1Lymphohistiocytosis, Hemophagocytic 1Leukemia, Myelomonocytic, Juvenile 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid, Chronic-Phase 1Leukemia, Myeloid, Accelerated Phase 1Leukemia, Myeloid 1Histiocytosis, Langerhans-Cell 1Eosinophilia 1

Interventions

trametinib 1dabrafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Has announcements × Neurofibroma, Plexiform × Myeloid × Clear all
NCT02124772 2021-07-14

Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations

Novartis

Phase 1/2 Completed
139 enrolled 42 charts 1 FDA
CNSMyeloid

Histiocytosis, Langerhans-Cell, Neoplasms, Neuroblastoma, Neurofibroma, Plexiform

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