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Phase

Phase 1 4Phase 2 2Phase 3 1Phase 1/2 1

Status

Terminated 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Genitourinary 383Breast 48Gastrointestinal 45Gynecologic 42Thoracic 36Head & Neck 26Dermatologic 18Sarcoma 11CNS 11Lymphoid 6Other hematologic neoplasm 4NET 4Endocrine 4Plasma cell 3Myeloid 1

Conditions

Myelodysplastic Syndromes 212Leukemia, Myeloid, Acute 178Leukemia 89Precursor Cell Lymphoblastic Leukemia-Lymphoma 86Leukemia, Myelogenous, Chronic, BCR-ABL Positive 81Myeloproliferative Disorders 61Leukemia, Myelomonocytic, Chronic 61Lymphoma, Non-Hodgkin 48Multiple Myeloma 43Primary Myelofibrosis 41Hodgkin Disease 37Lymphoma 36Blast Crisis 32Leukemia, Lymphocytic, Chronic, B-Cell 29Hematologic Neoplasms 29Polycythemia Vera 26Leukemia, Myeloid, Chronic-Phase 26Leukemia, Myeloid, Accelerated Phase 26Lymphoma, Mantle-Cell 24Thrombocythemia, Essential 22Lymphoma, Follicular 21Lymphoma, Large B-Cell, Diffuse 20Burkitt Lymphoma 20Anemia, Refractory, with Excess of Blasts 20Myelodysplastic-Myeloproliferative Diseases 19Recurrence 18Congenital Abnormalities 18Neoplasms, Plasma Cell 16Lymphoma, B-Cell, Marginal Zone 16Lymphoma, Large-Cell, Immunoblastic 15

Interventions

ruxolitinib 1rucaparib 1abiraterone 1Paclitaxel 1INCB057643 1Gemcitabine 1Azacitidine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Prostatic Neoplasms × Myeloid × Clear all
NCT02711137 2025-10-21

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Incyte Corporation

Phase 1/2 Terminated
137 enrolled 31 charts
BreastCNSGastrointestinalGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Primary Myelofibrosis

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