Announcements Trials
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Phase

Phase 1 2Phase NA 1

Status

Completed 2

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Lymphoid 12Genitourinary 9Plasma cell 6Other hematologic neoplasm 5Thoracic 2Sarcoma 2Myeloid 2Gastrointestinal 2Dermatologic 2Head & Neck 1Gynecologic 1CNS 1Breast 1

Conditions

Myelodysplastic Syndromes 382Leukemia, Myeloid, Acute 356Precursor Cell Lymphoblastic Leukemia-Lymphoma 184Leukemia 149Leukemia, Myelogenous, Chronic, BCR-ABL Positive 147Leukemia, Myelomonocytic, Chronic 128Myeloproliferative Disorders 114Leukemia, Lymphocytic, Chronic, B-Cell 100Primary Myelofibrosis 99Multiple Myeloma 89Lymphoma, Non-Hodgkin 89Hodgkin Disease 76Blast Crisis 68Lymphoma 62Leukemia, Myeloid, Chronic-Phase 58Lymphoma, Large B-Cell, Diffuse 53Lymphoma, Mantle-Cell 52Lymphoma, Follicular 52Burkitt Lymphoma 52Hematologic Neoplasms 51Leukemia, Myeloid, Accelerated Phase 50Congenital Abnormalities 47Polycythemia Vera 45Lymphoma, B-Cell, Marginal Zone 44Thrombocythemia, Essential 43Lymphoma, Large-Cell, Immunoblastic 43Anemia, Refractory, with Excess of Blasts 42Myelodysplastic-Myeloproliferative Diseases 41Neoplasms, Plasma Cell 40Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 40

Interventions

ripretinib 1pevonedistat 1Azacitidine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Renal Insufficiency × Myeloid × Clear all
NCT03814005 2024-09-05

A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Takeda

Phase 1 Completed
17 enrolled 33 charts
MyeloidOther hematologic neoplasm

Liver Diseases, Myelodysplastic Syndromes, Neoplasms, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Renal Insufficiency

NCT02571036 2023-12-13

A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies

Deciphera Pharmaceuticals, LLC

Phase 1 Completed
282 enrolled
CNSDermatologicGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmSarcomaThoracic

Mast Cell Activation Disorders, Carcinoma, Non-Small-Cell Lung, Glioma, Leukemia, Mast-Cell, Melanoma, Neoplasms, Germ Cell and Embryonal, Penile Neoplasms, Sarcoma, Mastocytosis, Systemic, Gastrointestinal Stromal Tumors, Renal Insufficiency

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