Announcements Trials
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Phase

Phase 2 1

Status

Completed 114Recruiting 29Terminated 24Active not recruiting 13Withdrawn 7Unknown 6Not yet recruiting 3Suspended 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Myeloid 1

Conditions

Myelodysplastic Syndromes 11Leukemia, Myeloid, Acute 7Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Myeloproliferative Disorders 3Primary Myelofibrosis 2Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2Leukemia 2Thrombocythemia, Essential 1Stomach Neoplasms 1Recurrence 1Rectal Neoplasms 1Polycythemia Vera 1Neoplasms 1Neoplasm, Residual 1Neoplasm Metastasis 1Myelodysplastic-Myeloproliferative Diseases 1Multiple Myeloma 1Lymphoma, Non-Hodgkin 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Lymphocytic, Chronic, B-Cell 1Hodgkin Disease 1Histiocytosis, Non-Langerhans-Cell 1Histiocytosis, Langerhans-Cell 1Hereditary Sensory and Autonomic Neuropathies 1Hematologic Neoplasms 1GATA2 Deficiency 1Esophageal Neoplasms 1Colorectal Neoplasms 1Castleman Disease 1Anemia, Refractory, with Excess of Blasts 1

Interventions

iadademstat 1decitabine and cedazuridine drug combination 1Specimen Handling 1Biopsy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Suspended × Thrombocythemia, Essential × Myeloid × Clear all
NCT06661915 2026-05-29

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

National Cancer Institute (NCI)

Phase 2 Suspended
62 enrolled
Myeloid

Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Myelodysplastic-Myeloproliferative Diseases, Primary Myelofibrosis

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