Announcements Trials
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Phase

Phase 2 1

Status

Active not recruiting 1

Sponsor Class

INDUSTRY 4OTHER 3NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 55Endocrine 31CNS 11Gastrointestinal 9Genitourinary 8Dermatologic 8Thoracic 7Breast 7Gynecologic 6Sarcoma 4Lymphoid 3Other hematologic neoplasm 2Plasma cell 1Other solid neoplasm 1NET 1Myeloid 1

Conditions

Myelodysplastic Syndromes 114Leukemia, Myeloid, Acute 103Leukemia 83Precursor Cell Lymphoblastic Leukemia-Lymphoma 79Myeloproliferative Disorders 65Leukemia, Myelogenous, Chronic, BCR-ABL Positive 61Leukemia, Myelomonocytic, Chronic 60Lymphoma, Non-Hodgkin 56Leukemia, Lymphocytic, Chronic, B-Cell 53Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 41Blast Crisis 41Leukemia, Myeloid, Chronic-Phase 40Multiple Myeloma 39Hodgkin Disease 37Lymphoma 35Leukemia, Myeloid, Accelerated Phase 35Congenital Abnormalities 35Anemia, Refractory, with Excess of Blasts 35Primary Myelofibrosis 33Lymphoma, Follicular 33Lymphoma, Large B-Cell, Diffuse 32Burkitt Lymphoma 30Lymphoma, Mantle-Cell 29Myelodysplastic-Myeloproliferative Diseases 27Lymphoma, Large-Cell, Immunoblastic 27Lymphoma, B-Cell, Marginal Zone 27Polycythemia Vera 24Thrombocythemia, Essential 23Neuroblastoma 23Neoplasms, Plasma Cell 23

Interventions

tipifarnib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
NIH × Thyroid Neoplasms × Myeloid × Clear all
NCT04284774 2026-05-27

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

Phase 2 Active not recruiting
5 enrolled 9 charts
CNSDermatologicEndocrineGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Medulloblastoma, Melanoma, Wilms Tumor, Neuroblastoma, Pheochromocytoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Thyroid Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

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