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Phase 1 1

Status

Recruiting 1

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NIH 1

Study Type

Interventional 1

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Cancer Type

Gastrointestinal 4Breast 4Thoracic 3Gynecologic 3Plasma cell 2Head & Neck 2Genitourinary 2Endocrine 2Dermatologic 2Sarcoma 1Other hematologic neoplasm 1NET 1Myeloid 1Lymphoid 1

Conditions

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Myelodysplastic Syndromes 1Multiple Myeloma 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid, Acute 1Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1Hematologic Neoplasms 1

Interventions

Specimen Handling 15Biopsy 14fludarabine 12Cytarabine 11Cyclophosphamide 11fludarabine phosphate 10X-Rays 9Whole-Body Irradiation 9venetoclax 8Magnetic Resonance Spectroscopy 8Injections 8asciminib 7Azacitidine 7Nuclear Medicine Department, Hospital 6Mycophenolic Acid 6Busulfan 6decitabine and cedazuridine drug combination 5Tacrolimus 5Phantoms, Imaging 5Melphalan 5Granulocyte Colony-Stimulating Factor 5Filgrastim 5Cyclosporine 5CPX-351 5ruxolitinib 4ivosidenib 4Stem Cell Transplantation 4Peripheral Blood Stem Cell Transplantation 4Idarubicin 4Decitabine 4

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
aldesleukin × Myeloid × 30 days × Clear all
NCT06904066 2026-06-05

Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Recruiting
86 enrolled
LymphoidMyeloidOther hematologic neoplasmPlasma cell

Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

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