Announcements Trials
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Phase

Phase 2 40Phase 1 32Phase 1/2 17Phase 3 3Phase 2/3 3Phase NA 1Phase EARLY_PHASE1 1Phase 4 1

Status

Completed 2Unknown 1

Sponsor Class

INDUSTRY 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 21Myeloid 3Lymphoid 3Tumor-Agnostic 1Classical hematology 1

Conditions

Myelodysplastic Syndromes 3Leukemia, Myelomonocytic, Chronic 3Myeloproliferative Disorders 1Myelodysplastic-Myeloproliferative Diseases 1Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1Leukemia, Myeloid, Acute 1Leukemia 1Anemia, Refractory, with Excess of Blasts 1Anemia, Refractory 1

Interventions

Imatinib Mesylate 28nilotinib 21Cytarabine 21Methotrexate 16Hydroxyurea 15Cyclophosphamide 15Busulfan 15Peripheral Blood Stem Cell Transplantation 13ruxolitinib 11Etoposide 11Whole-Body Irradiation 10fludarabine phosphate 9fludarabine 9Tacrolimus 9Mycophenolic Acid 9Daunorubicin 9Idarubicin 8Radiotherapy 7Mitoxantrone 7Interferon-alpha 7Cyclosporine 6peginterferon alfa-2a 5bosutinib 5asciminib 5Melphalan 5Azacitidine 5merphos 4luspatercept 4Thioguanine 4Filgrastim 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 3 × Decitabine × Myeloid × Clear all
NCT03306264 2024-08-27

Study of ASTX727 vs IV Decitabine in Participants With MDS, CMML, and AML

Astex Pharmaceuticals, Inc.

Phase 3 Completed
227 enrolled 37 charts 1 FDA
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT00043381 2024-08-02

Decitabine Versus Supportive Care in Adults With Advanced-stage MDS

Astex Pharmaceuticals, Inc.

Phase 3 Completed
160 enrolled
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT00043134 2010-04-13

Low-Dose Decitabine Compared With Standard Supportive Care in Treating Older Patients With Myelodysplastic Syndrome

National Cancer Institute (NCI)

Phase 3 Unknown
220 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

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