Clinical Trials Browser

luspatercept × Myeloid × Clear all

NCT05564390 2026-06-05

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Phase 2 Recruiting

2,000 enrolled

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute

NCT04064060 2026-05-28

A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

Phase 3 Recruiting

665 enrolled

Myeloid

Myelodysplastic Syndromes, Myeloproliferative Disorders, beta-Thalassemia

NCT05732961 2026-05-05

Luspatercept for Anemia in Lower Risk MDS or Non-proliferative MDS/MPN Neoplasms

Phase 2 Active not recruiting

6 enrolled

Classical hematologyMyeloid

Anemia, Myelodysplastic Syndromes, Myeloproliferative Disorders

NCT07539779 2026-04-20

Luspatercept in Preventing Poor Erythroid Engraftment for Hematological Malignancies With Moderate to Severe Myelofibrosis

Phase 2/3 Not yet recruiting

196 enrolled

MyeloidOther hematologic neoplasm

Hematologic Neoplasms, Primary Myelofibrosis

NCT04717414 2025-07-10

INDEPENDENCE

Phase 3 Active not recruiting

313 enrolled

Classical hematologyMyeloid

Anemia, Myeloproliferative Disorders, Primary Myelofibrosis

NCT01688011 2025-07-03

Connect® Myeloid Disease Registry

Terminated

2,013 enrolled

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Primary Myelofibrosis

NCT06927232 2025-04-15

AZA+Lus VS AZA Monotherapy in HR-MDS

Phase 3 Not yet recruiting

86 enrolled

Myeloid

Higher-risk Myelodysplastic Syndrome

NCT05005182 2024-09-19

Luspatercept With or Without Hydroxyurea for the Treatment of Myelodysplastic/Myeloproliferative Neoplasms With Ring Sideroblasts and Thrombocytosis or Unclassifiable With Ring Sideroblasts

Phase 2 Terminated

3 enrolled 12 charts

Myeloid

Myeloproliferative Disorders, Thrombocytosis

NCT03194542 2023-08-24

A Safety and Efficacy Study to Evaluate Luspatercept in Subjects With Myeloproliferative Neoplasm-associated Myelofibrosis Who Have Anemia With and Without Red Blood Cell-transfusion Dependence

Phase 2 Completed

95 enrolled 32 charts

Classical hematologyMyeloid

Anemia, Primary Myelofibrosis

NCT02631070 2021-12-17

MEDALIST

Phase 3 Completed

229 enrolled 36 charts 1 FDA

Classical hematologyMyeloid

Anemia, Myelodysplastic Syndromes