Announcements Trials
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Phase

Phase 2 1

Status

Terminated 1Completed 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Observational 1Interventional 1

Sponsor

Cancer Type

Gastrointestinal 441Thoracic 50Gynecologic 37Breast 32Genitourinary 29Head & Neck 26Sarcoma 14Endocrine 9Dermatologic 9Other solid neoplasm 6NET 6CNS 5Plasma cell 2Other hematologic neoplasm 2Lymphoid 2Other neoplasm 1Myeloid 1

Conditions

Leukemia, Myeloid, Acute 3510Precursor Cell Lymphoblastic Leukemia-Lymphoma 2499Leukemia 2362Leukemia, Lymphocytic, Chronic, B-Cell 1992Myelodysplastic Syndromes 1412Hematologic Neoplasms 1385Lymphoma 1176Lymphoma, Non-Hodgkin 1079Leukemia, Myelogenous, Chronic, BCR-ABL Positive 863Lymphoma, Follicular 761Multiple Myeloma 739Lymphoma, Mantle-Cell 730Lymphoma, Large B-Cell, Diffuse 714Burkitt Lymphoma 692Lymphoma, B-Cell, Marginal Zone 645Hodgkin Disease 636Recurrence 627Leukemia, Myelomonocytic, Chronic 536Neoplasms 519Lymphoma, Large-Cell, Immunoblastic 451Myeloproliferative Disorders 445Leukemia, Myeloid, Chronic-Phase 437Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 414Congenital Abnormalities 411Waldenstrom Macroglobulinemia 360Blast Crisis 353Leukemia, Myeloid, Accelerated Phase 318Lymphoma, T-Cell, Cutaneous 311Primary Myelofibrosis 297Neoplasms, Plasma Cell 276

Interventions

trametinib 1dabrafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Biliary Tract Neoplasms × Other hematologic neoplasm × Clear all
NCT02034110 2023-08-21

Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers

Novartis

Phase 2 Completed
206 enrolled 40 charts 2 FDA
CNSEndocrineGastrointestinalHead & NeckOther hematologic neoplasmPlasma cellSarcoma

Nonseminomatous germ cell tumor, Biliary Tract Neoplasms, Glioma, Leukemia, Hairy Cell, Multiple Myeloma, Neoplasms, Gastrointestinal Stromal Tumors, Thyroid Carcinoma, Anaplastic

NCT02900248 2019-04-02

N1

CureOne

Terminated
23 enrolled
BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellSarcomaThoracic

Anus Neoplasms, Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Endometrial Neoplasms, Hematologic Neoplasms

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