Announcements Trials
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Phase

Phase 1 2

Status

Recruiting 1Completed 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Myeloid 3Other hematologic neoplasm 2Lymphoid 2

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 171Leukemia 91Burkitt Lymphoma 39Lymphoma 30Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 27Leukemia, Lymphocytic, Chronic, B-Cell 26Leukemia, Myeloid, Acute 25Multiple Myeloma 23Lymphoma, Follicular 19Lymphoma, Non-Hodgkin 18Leukemia, Biphenotypic, Acute 18Recurrence 16Lymphoma, B-Cell, Marginal Zone 14Hematologic Neoplasms 14Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 13Lymphoma, Large B-Cell, Diffuse 13Lymphoma, Mantle-Cell 12Lymphoma, Large-Cell, Immunoblastic 10Leukemia, Plasma Cell 10Hodgkin Disease 10Myelodysplastic Syndromes 9Waldenstrom Macroglobulinemia 8Leukemia, Myelomonocytic, Chronic 7Blast Crisis 7Lymphoma, T-Cell, Cutaneous 5Leukemia, Myelogenous, Chronic, BCR-ABL Positive 5Sezary Syndrome 4Mycosis Fungoides 4Lymphoma, T-Cell, Peripheral 4Lymphoma, Large-Cell, Anaplastic 4

Interventions

fludarabine phosphate 6Cyclophosphamide 6fludarabine 4Whole-Body Irradiation 4Mycophenolic Acid 4tagraxofusp 3Thiotepa 3Methotrexate 3Cyclosporine 3venetoclax 2Tacrolimus 2Specimen Handling 2Peripheral Blood Stem Cell Transplantation 2Dexamethasone 2Cytarabine 2Cyclosporins 2Calcium Dobesilate 2Azacitidine 2merphos 1lorvotuzumab mertansine 1dexamethasone acetate 1dexamethasone 21-phosphate 1auricularum 1X-Rays 1Vincristine 1Sirolimus 1Salvia hispanica seed extract 1Rituximab 1Ranitidine 1Nivolumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Blastic Plasmacytoid Dendritic Cell Neoplasm × Dexamethasone × Other hematologic neoplasm × Clear all
NCT04681105 2026-01-28

Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies

City of Hope Medical Center

Phase 1 Completed
13 enrolled
LymphoidMyeloidOther hematologic neoplasm

Blastic Plasmacytoid Dendritic Cell Neoplasm, Burkitt Lymphoma, Hodgkin Disease, Leukemia, Hairy Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Hematologic Neoplasms, Mastocytosis, Systemic, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT05476770 2024-12-06

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Therapeutic Advances in Childhood Leukemia Consortium

Phase 1 Recruiting
54 enrolled
LymphoidMyeloidOther hematologic neoplasm

Blastic Plasmacytoid Dendritic Cell Neoplasm, Hodgkin Disease, Leukemia, Biphenotypic, Acute, Lymphoma, B-Cell, Lymphoma, T-Cell, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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