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Phase

Phase NA 12Phase 1 12Phase 2 3Phase 1/2 2Phase EARLY_PHASE1 1Phase 4 1Phase 3 1Phase 2/3 1

Status

Terminated 1Completed 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 169Sarcoma 52Breast 18Thoracic 17Dermatologic 12Genitourinary 5Head & Neck 4Gastrointestinal 4Other hematologic neoplasm 2Gynecologic 2Myeloid 1Lymphoid 1Endocrine 1

Conditions

Leukemia, Myeloid, Acute 481Leukemia 287Precursor Cell Lymphoblastic Leukemia-Lymphoma 249Leukemia, Lymphocytic, Chronic, B-Cell 235Myelodysplastic Syndromes 200Lymphoma 148Lymphoma, Non-Hodgkin 143Hematologic Neoplasms 139Recurrence 109Lymphoma, Mantle-Cell 102Lymphoma, Follicular 100Lymphoma, Large B-Cell, Diffuse 96Multiple Myeloma 82Leukemia, Myelogenous, Chronic, BCR-ABL Positive 81Leukemia, Myelomonocytic, Chronic 77Lymphoma, B-Cell, Marginal Zone 75Burkitt Lymphoma 72Hodgkin Disease 69Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 52Lymphoma, B-Cell 50Neoplasms 47Waldenstrom Macroglobulinemia 46Myeloproliferative Disorders 44Blast Crisis 41Lymphoma, Large-Cell, Immunoblastic 38Leukemia, Myeloid, Chronic-Phase 35Leukemia, B-Cell 34Leukemia, Myeloid, Accelerated Phase 33Congenital Abnormalities 32Leukemia, Biphenotypic, Acute 31

Interventions

bintrafusp alfa protein, human 1N-(2,3-dihydroxypropyl)-1-((2-fluoro-4-iodophenyl)amino)isonicotinamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1/2 × Brain Neoplasms × Other hematologic neoplasm × Clear all
NCT04789668 2026-03-18

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

M.D. Anderson Cancer Center

Phase 1/2 Terminated
8 enrolled 13 charts
BreastCNSDermatologicOther hematologic neoplasmThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Hematologic Neoplasms, Triple Negative Breast Neoplasms

NCT02541370 2019-12-17

Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133

Chinese PLA General Hospital

Phase 1/2 Completed
20 enrolled
BreastCNSGastrointestinalGynecologicOther hematologic neoplasm

Brain Neoplasms, Breast Neoplasms, Leukemia, Lymphoid, Liver Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

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