Announcements Trials
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Phase

Phase NA 2Phase 2 1

Status

Recruiting 1Enrolling by invitation 1Completed 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

Plasma cell 5Lymphoid 4Other hematologic neoplasm 3

Conditions

Leukemia, Myeloid, Acute 441Precursor Cell Lymphoblastic Leukemia-Lymphoma 242Hematologic Neoplasms 220Leukemia, Lymphocytic, Chronic, B-Cell 186Myelodysplastic Syndromes 162Leukemia 131Lymphoma 92Lymphoma, Non-Hodgkin 82Leukemia, Myelogenous, Chronic, BCR-ABL Positive 73Multiple Myeloma 69Recurrence 59Leukemia, Myelomonocytic, Chronic 58Neoplasms 54Leukemia, Biphenotypic, Acute 48Burkitt Lymphoma 48Myeloproliferative Disorders 46Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 43Lymphoma, Large B-Cell, Diffuse 43Lymphoma, Mantle-Cell 41Hodgkin Disease 39Lymphoma, Follicular 34Lymphoma, B-Cell 33Lymphoma, B-Cell, Marginal Zone 27Leukemia, B-Cell 27Waldenstrom Macroglobulinemia 26Anemia, Refractory, with Excess of Blasts 25Primary Myelofibrosis 24Myelodysplastic-Myeloproliferative Diseases 21Leukemia, Myeloid, Chronic-Phase 19Hematologic Diseases 19

Interventions

siltuximab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Cytokine Release Syndrome × Other hematologic neoplasm × 90 days × Clear all
NCT04975555 2026-06-03

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

University of Alabama at Birmingham

Phase 2 Completed
24 enrolled 8 charts
LymphoidOther hematologic neoplasmPlasma cell

Cytokine Release Syndrome, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07499128 2026-06-01

Continuous Temperature Monitoring (CTM) for Cytokine Release Syndrome (CRS), an Immune-Related Adverse Event

National Institutes of Health Clinical Center (CC)

Phase NA Enrolling by invitation
136 enrolled
LymphoidOther hematologic neoplasmPlasma cell

Cytokine Release Syndrome, Lymphoma, Multiple Myeloma, Neoplasms, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06377059 2026-05-15

Early Detection of Complications During Immunotherapy for Haematological Malignancy

Rigshospitalet, Denmark

Phase NA Recruiting
100 enrolled
Other hematologic neoplasm

Cytokine Release Syndrome, Hematologic Neoplasms

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