Announcements Trials
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Phase

Phase 3 2

Status

Active not recruiting 2

Sponsor Class

NIH 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Lymphoid 2Myeloid 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 87Leukemia 49Leukemia, Biphenotypic, Acute 14Burkitt Lymphoma 14Lymphoma 13Leukemia, Myeloid, Acute 10Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 8Recurrence 5Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 4Myelodysplastic Syndromes 4Neoplasm, Residual 3Lymphoma, Non-Hodgkin 3Anemia, Refractory, with Excess of Blasts 3Myeloproliferative Disorders 2Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, Large B-Cell, Diffuse 2Leukemia, Myelomonocytic, Chronic 2Leukemia, Monocytic, Acute 2Leukemia, Erythroblastic, Acute 2Leukemia, Eosinophilic, Acute 2Down Syndrome 2Dendritic Cell Sarcoma, Interdigitating 2Anemia, Refractory 2Thrombocytopenia 1Sarcoma, Myeloid 1Neutropenia 1Myelodysplastic-Myeloproliferative Diseases 1Lymphoma, Mantle-Cell 1Lymphoma, Follicular 1Lymphoma, B-Cell, Marginal Zone 1

Interventions

Cytarabine 5Vincristine 3Thioguanine 3Methotrexate 3Mercaptopurine 3Daunorubicin 3Cyclophosphamide 3prednylidene 2pegaspargase 2merphos 2dexamethasone acetate 2dexamethasone 21-phosphate 2azathiopurine 2auricularum 2asparaginase erwinia chrysanthemi recombinant 2Prednisolone 2Leucovorin 2Etoposide 2Doxorubicin 2Dexamethasone 2Calcium Dobesilate 2Asparaginase 2deltacortene 1blinatumomab 1Radiotherapy 1Radiation 1Prednisone 1N,N-dicyclohexyl-isoborneol-10-sulfonamide 1Mitoxantrone 1Methylprednisolone 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Down Syndrome × Asparaginase × Other hematologic neoplasm × Clear all
NCT03914625 2026-05-27

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

National Cancer Institute (NCI)

Phase 3 Active not recruiting
6,720 enrolled
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Down Syndrome, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

NCT02521493 2025-08-01

Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

Children's Oncology Group

Phase 3 Active not recruiting
280 enrolled 13 charts
MyeloidOther hematologic neoplasm

Down Syndrome, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute

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