Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Completed 2

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Myeloid 5Other hematologic neoplasm 2Other neoplasm 1

Conditions

Leukemia, Myeloid, Acute 23Precursor Cell Lymphoblastic Leukemia-Lymphoma 18Leukemia 17Myelodysplastic Syndromes 14Primary Myelofibrosis 10Leukemia, Myelogenous, Chronic, BCR-ABL Positive 10Myeloproliferative Disorders 9Leukemia, Myelomonocytic, Chronic 8Leukemia, Lymphocytic, Chronic, B-Cell 6Hematologic Neoplasms 6Graft vs Host Disease 6Myelodysplastic-Myeloproliferative Diseases 5Leukemia, Myeloid, Chronic-Phase 5Thrombocythemia, Essential 4Recurrence 4Polycythemia Vera 4Neoplasms 4Multiple Myeloma 4Lymphoma 4Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma, T-Cell 3Leukemia, Prolymphocytic, T-Cell 3Prostatic Neoplasms 2Pancreatic Neoplasms 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, Non-Hodgkin 2Leukemia, Myeloid, Accelerated Phase 2Leukemia, Monocytic, Acute 2Leukemia, Large Granular Lymphocytic 2

Interventions

Cyclophosphamide 13fludarabine 11Mycophenolic Acid 9Busulfan 8fludarabine phosphate 7Tacrolimus 7pirtobrutinib 6Whole-Body Irradiation 6Rituximab 6Melphalan 6Imatinib Mesylate 5Bone Marrow Transplantation 5ponatinib 4Mesna 4Granulocyte Colony-Stimulating Factor 4Azacitidine 4venetoclax 3nilotinib 3lintuzumab 3Stem Cell Transplantation 3Sirolimus 3Platelet Transfusion 3Methotrexate 3Cytarabine 3Cyclosporine 3Alemtuzumab 3vosaroxin 2ruxolitinib 2ibrutinib 2Thiotepa 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Hematologic Diseases × ruxolitinib × Other hematologic neoplasm × Clear all
NCT02158858 2026-06-04

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

Constellation Pharmaceuticals

Phase 1/2 Completed
336 enrolled 61 charts
MyeloidOther hematologic neoplasmOther neoplasm

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Myelodysplastic-Myeloproliferative Diseases, Primary Myelofibrosis

NCT01369498 2020-07-01

Efficacy and Safety of Simtuzumab in Adults With Primary, Post Polycythemia Vera or Post Essential Thrombocythemia Myelofibrosis

Gilead Sciences

Phase 2 Completed
54 enrolled 16 charts
MyeloidOther hematologic neoplasm

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Primary Myelofibrosis

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