Clinical Trials Browser

Immunologic Deficiency Syndromes × Other hematologic neoplasm × Clear all

NCT06689800 2026-06-04

Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy

Phase NA Recruiting

60 enrolled

Classical hematologyOther hematologic neoplasm

Anemia, Aplastic, Anemia, Sickle Cell, Immunologic Deficiency Syndromes, Metabolic Diseases, Hematologic Neoplasms

NCT06839456 2026-04-15

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

Phase 1/2 Recruiting

100 enrolled

Classical hematologyLymphoidOther hematologic neoplasm

Bone Marrow Failure Disorders, Congenital Bone Marrow Failure Syndromes, Anemia, Refractory, with Excess of Blasts, Hemoglobinopathies, Immunologic Deficiency Syndromes, Leukemia, Lymphoma, Non-Hodgkin, Metabolism, Inborn Errors

NCT02356653 2026-02-20

ExpMACs

Phase EARLY_PHASE1 Recruiting

100 enrolled

Other hematologic neoplasm

Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome, Bone Marrow Failure Disorders, Immunologic Deficiency Syndromes, Leukemia, Metabolism, Inborn Errors

NCT01881334 2025-11-20

Expanded Access to T-cell Depleted Haplo-Identical Stem Cells for Patients Receiving Haplo-Identical and Unrelated Cord Blood Transplants

Available

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Adrenoleukodystrophy, Anemia, Aplastic, Anemia, Sickle Cell, Immunologic Deficiency Syndromes, Lymphoma, Metabolic Diseases, Myelodysplastic Syndromes, Thalassemia, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05655546 2025-08-08

ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals

Phase NA Terminated

2,117 enrolled 6 charts

LymphoidOther hematologic neoplasmPlasma cell

COVID-19, Graft vs Host Disease, Immunologic Deficiency Syndromes, Leukemia, Lymphoma, Multiple Myeloma, Neoplasms, HIV Infections

NCT03333486 2025-07-04

Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

Phase 2 Terminated

31 enrolled 18 charts

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

Congenital amegakaryocytic thrombocytopenia, Neutropenia, Severe Congenital, Autosomal Recessive 3, Shwachman-Diamond Syndrome, Anemia, Aplastic, Anemia, Sickle Cell, Granulomatous Disease, Chronic, Hemoglobinuria, Paroxysmal, Immunologic Deficiency Syndromes, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thalassemia, Thrombasthenia, Wiskott-Aldrich Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, B-Cell, Lymphoma, T-Cell, Anemia, Diamond-Blackfan, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

NCT03145545 2025-05-22

Expanded Access Protocol Using Alpha/Beta T and CD19+ Depleted PBSC

Available

Other hematologic neoplasm

Bone Marrow Failure Disorders, Immunologic Deficiency Syndromes, Leukemia

NCT02291965 2025-03-03

Blood Samples to Identify Biomarkers of Busulfan

Terminated

139 enrolled

LymphoidMyeloidOther hematologic neoplasmPlasma cell

Immunologic Deficiency Syndromes, Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes

NCT06475469 2024-06-26

Description of the Immune Deficiency in Patients With Untreated Chronic Lymphocytic Leukemia and Search for Predictive Factors of Infectious Risk

Phase NA Recruiting

75 enrolled

LymphoidOther hematologic neoplasm

Bronchiectasis, Immunologic Deficiency Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell

NCT03609840 2023-09-21

Study of Thiotepa and TEPA Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients

Completed

25 enrolled

Classical hematologyOther hematologic neoplasm

Anemia, Sickle Cell, Fanconi Anemia, Hemoglobinopathies, Immunologic Deficiency Syndromes, Thalassemia, Hematologic Neoplasms

NCT03373656 2022-07-26

Vaccination for Children of H&O and Their Parents

Phase NA Unknown

300 enrolled

Other hematologic neoplasm

Immunologic Deficiency Syndromes, Hematologic Neoplasms

NCT00968864 2022-04-22

T-cell Depleted Alternative Donor Transplantation

Phase 2 Terminated

53 enrolled 14 charts

LymphoidMyeloidOther hematologic neoplasm

Bone Marrow Failure Disorders, Hemoglobinopathies, Immunologic Deficiency Syndromes, Lymphoma, Myelodysplastic Syndromes, Osteopetrosis, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01316549 2021-10-04

HCT

Completed

67 enrolled

Classical hematologyOther hematologic neoplasm

Anemia, Sickle Cell, Fanconi Anemia, Hemoglobinopathies, Immunologic Deficiency Syndromes, Thalassemia, Hematologic Neoplasms

NCT03609814 2021-10-04

Study of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT)

Completed

30 enrolled

Classical hematologyOther hematologic neoplasm

Anemia, Sickle Cell, Fanconi Anemia, Hemoglobinopathies, Immunologic Deficiency Syndromes, Thalassemia, Hematologic Neoplasms

NCT03609827 2021-10-04

Study of Melphalan Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients

Completed

25 enrolled

Classical hematologyOther hematologic neoplasm

Anemia, Sickle Cell, Fanconi Anemia, Hemoglobinopathies, Immunologic Deficiency Syndromes, Thalassemia, Hematologic Neoplasms

NCT01200017 2021-05-27

Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell Transplant

No longer available

Classical hematologyLymphoidMyeloidOther hematologic neoplasmOther neoplasm

Bone Marrow Failure Disorders, Cytopenia, Bone Diseases, Bone Diseases, Developmental, Bone Marrow Diseases, Graft vs Host Disease, Hematologic Diseases, Hemoglobinopathies, Immunologic Deficiency Syndromes, Immune System Diseases, Immunoproliferative Disorders, Leukemia, Leukemia, Lymphoid, Leukemia, Myeloid, Leukocyte Disorders, Lymphatic Diseases, Lymphoma, Lymphoproliferative Disorders, Musculoskeletal Diseases, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Osteochondrodysplasias, Osteopetrosis, Osteosclerosis, Pancytopenia, Precancerous Conditions, Preleukemia, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Genetic Diseases, Inborn, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00801931 2019-03-27

Double Cord Blood Transplant for Patients With Malignant and Non-malignant Disorders

Phase 1/2 Terminated

1 enrolled 8 charts

CNSClassical hematologyLymphoidOther hematologic neoplasm

Anemia, Immunologic Deficiency Syndromes, Leukemia, Lymphoma, Neuroblastoma

NCT01049854 2018-08-21

CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant

Phase 2 Completed

20 enrolled

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Bone Marrow Failure Disorders, Anemia, Sickle Cell, Immunologic Deficiency Syndromes, Leukemia, Lymphoma, Metabolism, Inborn Errors, Histiocytosis, beta-Thalassemia

NCT00179790 2017-03-06