Announcements Trials
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Phase

Phase 2 2

Status

Completed 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Classical hematology 1

Conditions

Leukemia 20Leukemia, Myeloid, Acute 17Precursor Cell Lymphoblastic Leukemia-Lymphoma 15Myelodysplastic Syndromes 8Lymphoma 7Leukemia, Myelomonocytic, Chronic 7Blast Crisis 7Leukemia, Myelomonocytic, Acute 6Leukemia, Monocytic, Acute 6Leukemia, Megakaryoblastic, Acute 6Leukemia, Erythroblastic, Acute 6Burkitt Lymphoma 6Anemia, Refractory, with Excess of Blasts 6Lymphoma, Non-Hodgkin 5Lymphoma, Large B-Cell, Diffuse 5Polycythemia Vera 4Lymphoma, Mantle-Cell 4Lymphoma, Large-Cell, Immunoblastic 4Lymphoma, Follicular 4Lymphoma, B-Cell, Marginal Zone 4Leukemia, Promyelocytic, Acute 4Leukemia, Lymphocytic, Chronic, B-Cell 4Hodgkin Disease 4Thrombocythemia, Essential 3Primary Myelofibrosis 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Myeloproliferative Disorders 3Congenital Abnormalities 3Recurrence 2Myelodysplastic-Myeloproliferative Diseases 2

Interventions

Cyclophosphamide 44fludarabine phosphate 39Peripheral Blood Stem Cell Transplantation 36Busulfan 33Antilymphocyte Serum 26Cyclosporine 25Tacrolimus 24Filgrastim 23Mycophenolic Acid 22Methotrexate 22Radiotherapy 21Melphalan 16Etoposide 15Cytarabine 15Whole-Body Irradiation 14Methylprednisolone 13Cord Blood Stem Cell Transplantation 12Biopsy 8Azacitidine 8Sirolimus 7Flow Cytometry 7Cyclosporins 7Alemtuzumab 7Thiotepa 6Specimen Handling 6Psychiatric Rehabilitation 6Decitabine 6sargramostim 5ruxolitinib 5Rituximab 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Myelodysplastic-Myeloproliferative Diseases × Topotecan × Other hematologic neoplasm × Clear all
NCT03289910 2026-04-13

Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

National Cancer Institute (NCI)

Phase 2 Active not recruiting
25 enrolled 15 charts
MyeloidOther hematologic neoplasm

Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT00053287 2010-06-10

Fludarabine/Carboplatin/Topotecan w/Thalidomide for Relapsed/Refractory AML, CML and MDS

Case Comprehensive Cancer Center

Phase 2 Completed
42 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Blast Crisis, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Leukemia, Promyelocytic, Acute, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

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