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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Plasma cell 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1Classical hematology 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 6Leukemia, Myeloid, Acute 5Leukemia, Myelomonocytic, Chronic 4Leukemia, Myelomonocytic, Acute 3Congenital Abnormalities 3Sezary Syndrome 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Myeloproliferative Disorders 2Myelodysplastic Syndromes 2Mycosis Fungoides 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, Non-Hodgkin 2Lymphoma, Mantle-Cell 2Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, Large-Cell, Anaplastic 2Lymphoma, Large B-Cell, Diffuse 2Lymphoma, Follicular 2Lymphoma, B-Cell, Marginal Zone 2Leukemia, Promyelocytic, Acute 2Leukemia, Monocytic, Acute 2Leukemia, Megakaryoblastic, Acute 2Leukemia, Lymphocytic, Chronic, B-Cell 2Leukemia, Erythroblastic, Acute 2Leukemia 2Intraocular Lymphoma 2Immunoblastic Lymphadenopathy 2Burkitt Lymphoma 2Blast Crisis 2Anemia, Refractory, with Excess of Blasts 2Wilms Tumor 1

Interventions

Cyclophosphamide 61fludarabine phosphate 52Peripheral Blood Stem Cell Transplantation 41Busulfan 41Tacrolimus 36Antilymphocyte Serum 34Mycophenolic Acid 33Radiotherapy 30Melphalan 27Filgrastim 27Cyclosporine 25Methotrexate 23Whole-Body Irradiation 21fludarabine 20Methylprednisolone 18Etoposide 17Cord Blood Stem Cell Transplantation 15sargramostim 10Cytarabine 10Rituximab 9Alemtuzumab 9Sirolimus 8Granulocyte Colony-Stimulating Factor 8Epoetin Alfa 7Carmustine 7Stem Cell Transplantation 6Psychiatric Rehabilitation 6Prednisone 6Flow Cytometry 6Trimethoprim, Sulfamethoxazole Drug Combination 5

Date Range

30 days90 days1 yearAll

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Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Neoplasms, Plasma Cell × entinostat × Other hematologic neoplasm × Clear all
NCT00015925 2010-03-10

MS-275 in Treating Patients With Hematologic Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 1 Completed
Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Blast Crisis, Leukemia, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Promyelocytic, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

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