Announcements Trials
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Phase

Phase 2 2Phase 1/2 1

Status

Recruiting 2Active not recruiting 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 62Sarcoma 8Dermatologic 5Other hematologic neoplasm 3Lymphoid 2Gastrointestinal 2Classical hematology 2Thoracic 1Other solid neoplasm 1Myeloid 1Gynecologic 1Endocrine 1Breast 1

Conditions

Leukemia, Myeloid, Acute 885Precursor Cell Lymphoblastic Leukemia-Lymphoma 511Hematologic Neoplasms 464Leukemia, Lymphocytic, Chronic, B-Cell 392Leukemia 336Myelodysplastic Syndromes 330Lymphoma 207Lymphoma, Non-Hodgkin 191Multiple Myeloma 146Leukemia, Myelogenous, Chronic, BCR-ABL Positive 142Recurrence 138Neoplasms 135Leukemia, Myelomonocytic, Chronic 112Burkitt Lymphoma 93Lymphoma, Mantle-Cell 92Lymphoma, Follicular 92Lymphoma, Large B-Cell, Diffuse 91Myeloproliferative Disorders 84Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 83Leukemia, Biphenotypic, Acute 81Lymphoma, B-Cell, Marginal Zone 75Hodgkin Disease 72Lymphoma, B-Cell 64Waldenstrom Macroglobulinemia 54Primary Myelofibrosis 54Leukemia, B-Cell 52Anemia, Refractory, with Excess of Blasts 46Leukemia, Myeloid, Chronic-Phase 41Hematologic Diseases 37Lymphoma, T-Cell 33

Interventions

trametinib 2fludarabine 2thymoglobulin 1omipalisib 1fludarabine phosphate 1Rituximab 1Melphalan 1Levetiracetam 1Injections 1Cytarabine 1Cyclophosphamide 1Busulfan 1Biopsy 1Azacitidine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Neurofibromatosis 1 × Other hematologic neoplasm × 1 year × Clear all
NCT03190915 2026-05-27

Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia

National Cancer Institute (NCI)

Phase 2 Active not recruiting
10 enrolled 11 charts
CNSOther hematologic neoplasm

Neurofibromatosis 1, Leukemia, Myelomonocytic, Juvenile

NCT05849662 2026-04-15

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

Therapeutic Advances in Childhood Leukemia Consortium

Phase 1/2 Recruiting
58 enrolled
CNSOther hematologic neoplasm

Neurofibromatosis 1, Leukemia, Myelomonocytic, Juvenile

NCT05735717 2026-04-06

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Masonic Cancer Center, University of Minnesota

Phase 2 Recruiting
70 enrolled
CNSClassical hematologyLymphoidOther hematologic neoplasm

Chromosome 7, monosomy, Anemia, Refractory, with Excess of Blasts, Chromosome Aberrations, Influenza, Human, Neurofibromatosis 1, Leukemia, Myeloid, Acute, beta-Thalassemia, Neoplasm, Residual, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile

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