Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Recruiting 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2CNS 2Lymphoid 1Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 246Precursor Cell Lymphoblastic Leukemia-Lymphoma 147Myelodysplastic Syndromes 141Leukemia, Lymphocytic, Chronic, B-Cell 140Leukemia 128Lymphoma 80Hematologic Neoplasms 77Lymphoma, Non-Hodgkin 73Leukemia, Myelogenous, Chronic, BCR-ABL Positive 67Hodgkin Disease 55Multiple Myeloma 54Myeloproliferative Disorders 37Recurrence 34Lymphoma, Mantle-Cell 29Graft vs Host Disease 28Burkitt Lymphoma 28Lymphoma, B-Cell 26Lymphoma, Follicular 25Leukemia, Biphenotypic, Acute 25Anemia, Refractory, with Excess of Blasts 23Leukemia, Myelomonocytic, Chronic 22Lymphoma, Large B-Cell, Diffuse 21Neoplasms, Plasma Cell 20Lymphoma, B-Cell, Marginal Zone 20Primary Myelofibrosis 19Leukemia, Prolymphocytic 14Leukemia, Myeloid 13Anemia, Aplastic 13Neoplasms 12Leukemia, B-Cell 12

Interventions

trametinib 2fludarabine 2thymoglobulin 1omipalisib 1fludarabine phosphate 1Rituximab 1Melphalan 1Levetiracetam 1Injections 1Cytarabine 1Cyclophosphamide 1Busulfan 1Biopsy 1Azacitidine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Neurofibromatosis 1 × fludarabine × Other hematologic neoplasm × Clear all
NCT05849662 2026-04-15

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

Therapeutic Advances in Childhood Leukemia Consortium

Phase 1/2 Recruiting
58 enrolled
CNSOther hematologic neoplasm

Neurofibromatosis 1, Leukemia, Myelomonocytic, Juvenile

NCT05735717 2026-04-06

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Masonic Cancer Center, University of Minnesota

Phase 2 Recruiting
70 enrolled
CNSClassical hematologyLymphoidOther hematologic neoplasm

Chromosome 7, monosomy, Anemia, Refractory, with Excess of Blasts, Chromosome Aberrations, Influenza, Human, Neurofibromatosis 1, Leukemia, Myeloid, Acute, beta-Thalassemia, Neoplasm, Residual, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile

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