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Phase

Phase 2 1Phase 1/2 1

Status

Recruiting 2Unknown 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 26Sarcoma 4Dermatologic 3Other hematologic neoplasm 2Lymphoid 2Gastrointestinal 2Endocrine 2Classical hematology 2Other solid neoplasm 1NET 1Myeloid 1Head & Neck 1Gynecologic 1Breast 1

Conditions

Leukemia, Myeloid, Acute 541Precursor Cell Lymphoblastic Leukemia-Lymphoma 310Hematologic Neoplasms 264Leukemia 179Myelodysplastic Syndromes 170Leukemia, Lymphocytic, Chronic, B-Cell 168Lymphoma 101Lymphoma, Non-Hodgkin 94Recurrence 84Neoplasms 83Multiple Myeloma 82Leukemia, Myelogenous, Chronic, BCR-ABL Positive 72Leukemia, Myelomonocytic, Chronic 61Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 58Burkitt Lymphoma 54Leukemia, Biphenotypic, Acute 48Myeloproliferative Disorders 45Lymphoma, Follicular 43Lymphoma, Mantle-Cell 42Lymphoma, Large B-Cell, Diffuse 42Hodgkin Disease 34Lymphoma, B-Cell 32Lymphoma, B-Cell, Marginal Zone 30Leukemia, B-Cell 30Anemia, Refractory, with Excess of Blasts 30Primary Myelofibrosis 28Leukemia, Plasma Cell 23Waldenstrom Macroglobulinemia 22Neoplasm, Residual 21Leukemia, Myeloid, Chronic-Phase 21

Interventions

fludarabine 2trametinib 1thymoglobulin 1fludarabine phosphate 1Rituximab 1Melphalan 1Levetiracetam 1Injections 1Cytarabine 1Cyclophosphamide 1Busulfan 1Azacitidine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Recruiting × Neurofibromatosis 1 × Other hematologic neoplasm × Clear all
NCT05849662 2026-04-15

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

Therapeutic Advances in Childhood Leukemia Consortium

Phase 1/2 Recruiting
58 enrolled
CNSOther hematologic neoplasm

Neurofibromatosis 1, Leukemia, Myelomonocytic, Juvenile

NCT05735717 2026-04-06

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Masonic Cancer Center, University of Minnesota

Phase 2 Recruiting
70 enrolled
CNSClassical hematologyLymphoidOther hematologic neoplasm

Chromosome 7, monosomy, Anemia, Refractory, with Excess of Blasts, Chromosome Aberrations, Influenza, Human, Neurofibromatosis 1, Leukemia, Myeloid, Acute, beta-Thalassemia, Neoplasm, Residual, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile

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