Announcements Trials
Browse Landscape

Phase

Phase 1 2

Status

Completed 7Terminated 2Withdrawn 1Unknown 1

Sponsor Class

NIH 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 11Sarcoma 7Lymphoid 4Genitourinary 3Gastrointestinal 3Other hematologic neoplasm 2Gynecologic 2Endocrine 2Other solid neoplasm 1

Conditions

Leukemia, Myeloid, Acute 514Leukemia 340Leukemia, Lymphocytic, Chronic, B-Cell 322Precursor Cell Lymphoblastic Leukemia-Lymphoma 291Myelodysplastic Syndromes 235Lymphoma, Non-Hodgkin 173Lymphoma 162Leukemia, Myelogenous, Chronic, BCR-ABL Positive 139Hematologic Neoplasms 133Multiple Myeloma 121Lymphoma, Follicular 120Lymphoma, Large B-Cell, Diffuse 119Lymphoma, Mantle-Cell 118Recurrence 115Hodgkin Disease 99Burkitt Lymphoma 99Lymphoma, B-Cell, Marginal Zone 98Leukemia, Myelomonocytic, Chronic 78Congenital Abnormalities 78Leukemia, Myeloid, Chronic-Phase 68Neoplasms 67Myeloproliferative Disorders 66Lymphoma, Large-Cell, Immunoblastic 64Blast Crisis 59Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 57Waldenstrom Macroglobulinemia 53Primary Myelofibrosis 53Lymphoma, T-Cell, Cutaneous 52Leukemia, Myeloid, Accelerated Phase 50Neoplasms, Plasma Cell 48

Interventions

Topotecan 1Dexamethasone 1Calcium Dobesilate 12,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Terminated × Optic Nerve Glioma × Other hematologic neoplasm × Clear all
NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
129 enrolled
CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

NCT00112619 2011-06-30

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Pediatric Brain Tumor Consortium

Phase 1 Terminated
19 enrolled
CNSLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Neoplasms, Unknown Primary, Oligodendroglioma, Recurrence, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating, Meningeal Carcinomatosis

Data powered by HemOnc (CC BY 4.0) Colophon âš¡