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Phase

Phase 1 1

Status

Completed 7Terminated 2Withdrawn 1Unknown 1

Sponsor Class

NETWORK 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 4Sarcoma 2Other hematologic neoplasm 1Lymphoid 1

Conditions

Leukemia, Myeloid, Acute 140Leukemia 97Leukemia, Lymphocytic, Chronic, B-Cell 96Precursor Cell Lymphoblastic Leukemia-Lymphoma 90Hematologic Neoplasms 69Myelodysplastic Syndromes 55Lymphoma 47Lymphoma, Non-Hodgkin 45Lymphoma, B-Cell, Marginal Zone 34Leukemia, Myelogenous, Chronic, BCR-ABL Positive 34Lymphoma, Mantle-Cell 33Lymphoma, Follicular 33Burkitt Lymphoma 32Recurrence 28Lymphoma, Large B-Cell, Diffuse 28Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 24Hodgkin Disease 23Neoplasms 22Leukemia, Myelomonocytic, Chronic 22Multiple Myeloma 21Myeloproliferative Disorders 20Waldenstrom Macroglobulinemia 19Lymphoma, Large-Cell, Immunoblastic 19Leukemia, Myeloid, Chronic-Phase 17Congenital Abnormalities 16Primary Myelofibrosis 15Leukemia, Myeloid, Accelerated Phase 14Leukemia, Biphenotypic, Acute 14Mycosis Fungoides 13Lymphoma, T-Cell, Cutaneous 13

Interventions

N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L-ornithine 1Drug Therapy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Withdrawn × Optic Nerve Glioma × Other hematologic neoplasm × Clear all
NCT00458744 2014-08-08

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Children's Oncology Group

Phase 1 Withdrawn
CNSLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Recurrence, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating

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