Announcements Trials
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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other neoplasm 1Other hematologic neoplasm 1Myeloid 1

Conditions

Leukemia, Myeloid, Acute 23Precursor Cell Lymphoblastic Leukemia-Lymphoma 18Leukemia 17Myelodysplastic Syndromes 14Primary Myelofibrosis 10Leukemia, Myelogenous, Chronic, BCR-ABL Positive 10Myeloproliferative Disorders 9Leukemia, Myelomonocytic, Chronic 8Leukemia, Lymphocytic, Chronic, B-Cell 6Hematologic Neoplasms 6Graft vs Host Disease 6Myelodysplastic-Myeloproliferative Diseases 5Leukemia, Myeloid, Chronic-Phase 5Thrombocythemia, Essential 4Recurrence 4Polycythemia Vera 4Neoplasms 4Multiple Myeloma 4Lymphoma 4Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma, T-Cell 3Leukemia, Prolymphocytic, T-Cell 3Prostatic Neoplasms 2Pancreatic Neoplasms 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, Non-Hodgkin 2Leukemia, Myeloid, Accelerated Phase 2Leukemia, Monocytic, Acute 2Leukemia, Large Granular Lymphocytic 2

Interventions

Melphalan 4fludarabine 3fludarabine phosphate 2Whole-Body Irradiation 2Tacrolimus 2Peripheral Blood Stem Cell Transplantation 2Patient Reported Outcome Measures 2Mycophenolic Acid 2Mesna 2Cyclophosphamide 2Busulfan 2Bone Marrow Transplantation 2Alemtuzumab 2venetoclax 1spartalizumab 1sabatolimab 1ruxolitinib 1lintuzumab 1filanesib 1Stem Cell Transplantation 1Sertraline 1Sampling Studies 1Metformin 1Lenalidomide 1Decitabine 1Clofarabine 1CPI-0610 1Biopsy 1Azacitidine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Preleukemia × ruxolitinib × Other hematologic neoplasm × Clear all
NCT02158858 2026-06-04

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

Constellation Pharmaceuticals

Phase 1/2 Completed
336 enrolled 61 charts
MyeloidOther hematologic neoplasmOther neoplasm

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Myelodysplastic-Myeloproliferative Diseases, Primary Myelofibrosis

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