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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Lymphoid 1

Conditions

Lymphoma 9Leukemia, Lymphocytic, Chronic, B-Cell 9Lymphoma, Follicular 5Waldenstrom Macroglobulinemia 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Lymphoma, T-Cell, Peripheral 4Lymphoma, T-Cell, Cutaneous 4Lymphoma, Non-Hodgkin 4Lymphoma, Large B-Cell, Diffuse 4Lymphoma, B-Cell, Marginal Zone 4Leukemia, Myeloid, Acute 4Leukemia 4Lymphoma, Mantle-Cell 3Lymphoma, Large-Cell, Anaplastic 3Hematologic Neoplasms 3Congenital Abnormalities 3Burkitt Lymphoma 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Myeloproliferative Disorders 2Myelodysplastic-Myeloproliferative Diseases 2Myelodysplastic Syndromes 2Lymphoma, Extranodal NK-T-Cell 2Leukemia, Promyelocytic, Acute 2Leukemia, Myelomonocytic, Chronic 2Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 2Hodgkin Disease 2Urinary Bladder Neoplasms 1Thyroid Neoplasms 1Thrombocythemia, Essential 1Spinal Cord Neoplasms 1

Interventions

Cyclophosphamide 59fludarabine phosphate 53Peripheral Blood Stem Cell Transplantation 43Tacrolimus 40Mycophenolic Acid 36Busulfan 33Whole-Body Irradiation 32Antilymphocyte Serum 28Cyclosporine 27Methotrexate 25fludarabine 19Filgrastim 18Melphalan 17Radiotherapy 15Methylprednisolone 13Etoposide 12Cord Blood Stem Cell Transplantation 12thymoglobulin 11Sirolimus 11ruxolitinib 10Flow Cytometry 10Psychiatric Rehabilitation 9Azacitidine 9Stem Cell Transplantation 7Granulocyte Colony-Stimulating Factor 7Decitabine 7Therapeutics 6Imatinib Mesylate 6Cytarabine 6Cyclosporins 6

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Primary Myelofibrosis × romidepsin × Other hematologic neoplasm × Clear all
NCT00114257 2013-02-11

Decitabine and FR901228 in Treating Patients With Relapsed or Refractory Leukemia, Myelodysplastic Syndromes, or Myeloproliferative Disorders

National Cancer Institute (NCI)

Phase 1 Completed
36 enrolled
LymphoidMyeloidOther hematologic neoplasm

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Promyelocytic, Acute, Leukemia, Myelomonocytic, Chronic, Leukemia, Myelomonocytic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

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