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Phase

Phase 1 1

Status

Completed 22Recruiting 8Unknown 3Active not recruiting 3Terminated 2Suspended 1Not yet recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Gastrointestinal 13Breast 2Thoracic 1Sarcoma 1Plasma cell 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1Gynecologic 1Genitourinary 1Dermatologic 1

Conditions

Leukemia, Myeloid, Acute 20Precursor Cell Lymphoblastic Leukemia-Lymphoma 11Myelodysplastic Syndromes 10Leukemia 7Hematologic Neoplasms 7Leukemia, Lymphocytic, Chronic, B-Cell 5Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 4Lymphoma 4Neoplasms 3Immunoblastic Lymphadenopathy 3Recurrence 2Neoplasm Metastasis 2Myeloproliferative Disorders 2Lymphoma, T-Cell, Peripheral 2Lymphoma, T-Cell 2Lymphoma, Non-Hodgkin 2Lymphoma, Large-Cell, Anaplastic 2Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2Stomach Neoplasms 1Rectal Neoplasms 1Primary Myelofibrosis 1Pain, Intractable 1Neurotoxicity Syndromes 1Neoplasms by Histologic Type 1Neoplasm, Residual 1Multiple Myeloma 1Mucositis 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, B-Cell 1Leukemia-Lymphoma, Adult T-Cell 1

Interventions

vactosertib 1fludarabine phosphate 1aldesleukin 1Interleukin-2 1IL32 protein, human 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Suspended × Stomach Neoplasms × Other hematologic neoplasm × Clear all
NCT05400122 2025-11-12

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

Case Comprehensive Cancer Center

Phase 1 Suspended
12 enrolled
GastrointestinalLymphoidMyeloidOther hematologic neoplasmPlasma cell

Esophageal Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasm Metastasis, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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