Announcements Trials
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Phase

Phase 2/3 2Phase 2 1Phase 1 1

Status

Recruiting 1Not yet recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 3Endocrine 3Thoracic 2Plasma cell 2Other hematologic neoplasm 2Myeloid 2Gynecologic 2Gastrointestinal 2CNS 2Lymphoid 1Dermatologic 1

Conditions

Leukemia, Myeloid, Acute 59Precursor Cell Lymphoblastic Leukemia-Lymphoma 44Leukemia 29Hematologic Neoplasms 23Myelodysplastic Syndromes 18Lymphoma 16Neoplasms 15Leukemia, Myelogenous, Chronic, BCR-ABL Positive 12Lymphoma, Non-Hodgkin 9Leukemia, Lymphocytic, Chronic, B-Cell 7Graft vs Host Disease 7Neoplasms by Site 6Neoplasms by Histologic Type 6Multiple Myeloma 6Anemia, Refractory, with Excess of Blasts 6Recurrence 5Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 5Neoplasms, Plasma Cell 5Neoplasm, Residual 5Leukemia, Biphenotypic, Acute 5Infections 5Primary Myelofibrosis 4Lymphoproliferative Disorders 4Lymphoma, Mantle-Cell 4Lymphoma, Large B-Cell, Diffuse 4Leukemia, Myelomonocytic, Chronic 4Leukemia, Myeloid, Chronic-Phase 4Leukemia, Myeloid, Accelerated Phase 4Glioma 4Congenital Abnormalities 4

Interventions

trametinib 1dabrafenib 1cobimetinib 1Vemurafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2/3 × Thyroid Carcinoma, Anaplastic × Other hematologic neoplasm × Clear all
NCT07440290 2026-02-27

DETERMINE

Cancer Research UK

Phase 2/3 Not yet recruiting
30 enrolled
CNSEndocrineGastrointestinalGynecologicHead & NeckLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Glioma, Histiocytosis, Langerhans-Cell, Laryngeal Neoplasms, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT05768178 2025-11-24

DETERMINE

Cancer Research UK

Phase 2/3 Recruiting
30 enrolled
CNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Glioma, Laryngeal Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

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