Clinical Trials

Leukemia, Myeloid, Acute

NCT05313958 2023-07-27

SCCLG-M5

Phase 2/3 Unknown

43 enrolled

Leukemia, Monocytic, Acute

NCT02728050 2023-07-05

Filgrastim, Cladribine, Cytarabine, and Mitoxantrone With Sorafenib in Treating Patients With Newly-Diagnosed, Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

84 enrolled 28 charts

Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute

NCT01253070 2022-08-04

Sorafenib Tosylate and Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia

54 enrolled 10 charts

Leukemia, Promyelocytic, Acute, Leukemia, Myelomonocytic, Acute

NCT04326439 2022-06-15

AflacLL1901 (CHOA-AML)

8 enrolled 12 charts

Leukemia, Myeloid, Acute

NCT04752527 2021-11-15

Individualized Induction Therapy for Non-elderly Acute Myeloid Leukemia Patients With Adverse Risk Features

Phase 2 Unknown

42 enrolled

Leukemia, Myeloid, Acute

NCT01620216 2021-11-04

Targeted Therapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia

12 enrolled 12 charts

Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01445080 2021-02-02

Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

LymphoidMyeloidOther hematologic neoplasm

70 enrolled 26 charts

Blast Crisis, Recurrence, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile

NCT02779283 2020-05-26

Personalized Kinase Inhibitor Therapy Combined With Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia

7 enrolled

Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02530476 2020-03-31

Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid Leukemia

17 enrolled 14 charts

Leukemia, Recurrence, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT03170895 2020-03-30

Combination of Sorafenib and Omacetaxine Mepesuccinate in Newly Diagnosed or Relapsed/Refractory AML Carrying FLT3-ITD

5 enrolled

Leukemia, Myeloid, Acute

NCT02196857 2020-01-14

Sorafenib Plus 5-Azacitidine Initial Therapy of Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MS) With FLT3-ITD Mutation

16 enrolled 8 charts

Leukemia, Leukemia, Myeloid, Acute

NCT02474290 2019-08-26

Sorafenib for Prophylaxis of Leukemia Relapse in Allo-HSCT Recipients With FLT3-ITD Positive AML

Phase 2/3 Completed

202 enrolled

Leukemia, Myeloid, Acute

NCT00474929 2019-08-20

Sorafenib and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

DermatologicLymphoidOther hematologic neoplasmPlasma cell

103 enrolled 12 charts

Burkitt Lymphoma, Hodgkin Disease, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell

NCT02412475 2019-01-24

Epigenetic Reprogramming in Relapse AML

Phase 1 Terminated

3 enrolled

Leukemia, Myeloid, Acute

NCT00542971 2018-08-23

Phase I-II Study of Idarubicin, Cytarabine, and Sorafenib (BAY43-9006)

78 enrolled 6 charts

Leukemia, Leukemia, Myeloid, Acute

NCT01534260 2018-08-17

Phase I/II Study of Combination of Sorafenib, Vorinostat, and Bortezomib for the Treatment of Acute Myeloid Leukemia With Complex- or Poor-risk (Monosomy 5/7) Cytogenetics or FLT3-ITD Positive Genotype

37 enrolled 12 charts

Leukemia, Myeloid, Acute

NCT00908167 2018-01-12

Sorafenib in Combination With Cytarabine and Clofarabine in Patients With Refractory or Relapsed Hematologic Malignancies

LymphoidMyeloidOther hematologic neoplasm

44 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Promyelocytic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases

NCT02270788 2017-10-03

Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies

10 enrolled

Leukemia, Myeloid, Acute

NCT00943943 2017-03-29

Granulocyte-colony Stimulating Factor (G-CSF) and Plerixafor Plus Sorafenib for Acute Myelogenous Leukemia (AML) With FLT3 Mutations

33 enrolled

Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute

NCT01398501 2017-03-22

Sorafenib Maintenance Therapy for Patients With AML After Allogeneic Stem Cell Transplant

22 enrolled

Leukemia, Myeloid, Acute

NCT01183663 2016-06-03

Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX)

BreastCNSDermatologicGastrointestinalGenitourinaryOther hematologic neoplasmPlasma cell

180 enrolled

Breast Neoplasms, Carcinoma, Renal Cell, Colonic Neoplasms, Glioblastoma, Melanoma, Multiple Myeloma, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms

NCT01254890 2016-05-06

Sorafenib and 5-Azacitidine in Acute Leukemia + Myelodysplastic Syndrome

60 enrolled 5 charts

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT00510289 2016-04-19

Sorafenib in Myelodysplastic Syndrome

19 enrolled 9 charts

Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT00893373 2016-02-05

SORAML

276 enrolled

Leukemia, Myeloid, Acute

NCT01510756 2016-01-21

Sorafenib for the Treatment of Chronic Lymphocytic Leukemia (CLL)

4 enrolled 5 charts

Leukemia, Lymphocytic, Chronic, B-Cell

NCT00131937 2015-09-03

Sorafenib Tosylate in Treating Patients With Recurrent Aggressive Non-Hodgkin's Lymphoma

DermatologicLymphoidOther hematologic neoplasm

14 enrolled 7 charts

Immunoblastic Lymphadenopathy, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, T-Cell, Peripheral, Lymphoma, Large-Cell, Anaplastic, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT00217646 2015-04-28

Sorafenib in Treating Patients With Refractory or Relapsed Acute Leukemia, Myelodysplastic Syndromes, or Blastic Phase Chronic Myelogenous Leukemia

36 enrolled

Blast Crisis, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Promyelocytic, Acute, Leukemia, Myelomonocytic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00665990 2015-01-09

Phase I Study of Bevacizumab and Sorafenib Combined With Low Dose Cyclophosphamide in Patients With Refractory Solid Tumors and Leukemia

49 enrolled

Leukemia

NCT00661180 2014-12-23

ORACLE

10 enrolled

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT00875745 2014-09-18

Combination of Sorafenib and Vorinostat in Poor-risk Acute Myelogenous Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)

15 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Promyelocytic, Acute

NCT00303966 2014-05-07

Sorafenib in Treating Patients With Relapsed Chronic Lymphocytic Leukemia

5 enrolled 7 charts

Leukemia, Lymphocytic, Chronic, B-Cell

NCT01159301 2013-09-19

Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid Leukemia

Phase 1 Terminated

44 enrolled

Congenital Abnormalities, Blast Crisis, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

NCT00303797 2013-03-19

Sorafenib and Bortezomib in Treating Patients With Advanced Cancer

LymphoidOther hematologic neoplasmPlasma cell

50 enrolled

Multiple Myeloma, Leukemia, Lymphocytic, Chronic, B-Cell

NCT00131989 2013-01-09

Sorafenib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia

48 enrolled

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00118170 2013-01-07

Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function

LymphoidOther hematologic neoplasmPlasma cell

150 enrolled

Burkitt Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00373373 2009-08-19

Efficacy of Sorafenib Added to Standard Primary Therapy in Elderly Patients With Newly Diagnosed AML

200 enrolled