Announcements Trials
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Phase

Phase 3 2Phase 2 1Phase 1/2 1Phase 1 1

Status

Recruiting 13Active not recruiting 5Withdrawn 3Completed 2Terminated 1Not yet recruiting 1Approved for marketing 1

Sponsor Class

INDUSTRY 3OTHER 2

Study Type

Interventional 5

Sponsor

Cancer Type

Other hematologic neoplasm 5Sarcoma 3Myeloid 3Lymphoid 3Gastrointestinal 3Genitourinary 2CNS 2

Conditions

Leukemia, Myeloid, Acute 5Leukemia 2Myelodysplastic Syndromes 1

Interventions

venetoclax 75Cyclophosphamide 68Cytarabine 59fludarabine 49Azacitidine 44Specimen Handling 36fludarabine phosphate 35Rituximab 34Biopsy 30Methotrexate 28ibrutinib 27Daunorubicin 25Dexamethasone 24Vincristine 23obinutuzumab 21Etoposide 21Decitabine 21acalabrutinib 19Tacrolimus 19Dasatinib 19blinatumomab 18Melphalan 18Prednisone 16Mycophenolic Acid 16Granulocyte Colony-Stimulating Factor 16Busulfan 16Whole-Body Irradiation 15Doxorubicin 15Injections 14pegaspargase 13

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Active not recruiting × ivosidenib × Other hematologic neoplasm × Clear all
NCT02632708 2026-05-22

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

Servier

Phase 1 Active not recruiting
153 enrolled
Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT02677922 2026-02-19

A Study to Assess the Safety and Efficacy of Two Combinations of Isocitrate Dehydrogenase (IDH) Mutant Targeted Therapies Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) Harboring IDH Mutations Who Are Not Candidates to Receive Intensive Induction Chemotherapy

Celgene

Phase 1/2 Active not recruiting
130 enrolled 38 charts
Other hematologic neoplasm

Leukemia, Leukemia, Myeloid, Acute

NCT03173248 2025-11-10

AGILE

Servier

Phase 3 Active not recruiting
146 enrolled 11 charts 1 FDA
Other hematologic neoplasm

Leukemia, Leukemia, Myeloid, Acute

NCT03503409 2025-05-18

IDH1 (AG 120) Inhibitor in Patients With IDH1 Mutated Myelodysplastic Syndrome

Groupe Francophone des Myelodysplasies

Phase 2 Active not recruiting
68 enrolled
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT03839771 2024-10-02

HOVON150AML

Stichting Hemato-Oncologie voor Volwassenen Nederland

Phase 3 Active not recruiting
968 enrolled
Other hematologic neoplasm

Leukemia, Myeloid, Acute

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