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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Gastrointestinal 2Thoracic 1Other solid neoplasm 1

Conditions

Unspecified Adult Solid Tumor, Protocol Specific 13Wilms Tumor 1Small Cell Lung Carcinoma 1Retinoblastoma 1Recurrence 1Osteosarcoma 1Optic Nerve Glioma 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroblastoma 1Mesothelioma, Malignant 1Mesothelioma 1Medulloblastoma 1Familial ependymoma 1Esophageal Neoplasms 1Dendritic Cell Sarcoma, Interdigitating 1Carcinoma, Small Cell 1Carcinoma, Non-Small-Cell Lung 1Burkitt Lymphoma 1Astrocytoma 1

Interventions

pembrolizumab 10belinostat 2Plicamycin 2Decitabine 2Celecoxib 2tocilizumab 1spartalizumab 1obinutuzumab 1naptumomab estafenatox 1epacadostat 1entinostat 1durvalumab 1alvocidib 1Tetrahydrouridine 1Tablets 1Surgical Procedures, Operative 1Quality of Life 1Polymerase Chain Reaction 1Patient Reported Outcome Measures 1Nivolumab 1Molecular Diagnostic Techniques 1Microarray Analysis 1Levoleucovorin 1Leucovorin 1Ipilimumab 1Interleukin-2 1Immunotherapy, Adoptive 1Immunotherapy 1Immunoenzyme Techniques 1Gene Expression Profiling 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Esophageal Neoplasms × alvocidib × Other solid neoplasm × Clear all
NCT00094978 2019-12-12

Depsipeptide/Flavopiridol Infusion for Cancers of the Lungs, Esophagus, Pleura, Thymus or Mediastinum

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
23 enrolled
GastrointestinalOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Mesothelioma, Carcinoma, Small Cell, Small Cell Lung Carcinoma

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