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Phase

Phase 1/2 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other solid neoplasm 1

Conditions

Unspecified Adult Solid Tumor, Protocol Specific 141Mesothelioma, Malignant 49Mesothelioma 24Lung Neoplasms 18Unspecified Childhood Solid Tumor, Protocol Specific 15Carcinoma, Non-Small-Cell Lung 14Solitary Fibrous Tumor, Pleural 11Pancreatic Neoplasms 11Esophageal Neoplasms 11Sarcoma 10Ovarian Neoplasms 9Small Cell Lung Carcinoma 8Uterine Cervical Neoplasms 7Stomach Neoplasms 7Colonic Neoplasms 7Squamous Cell Carcinoma of Head and Neck 6Retinoblastoma 6Neoplasms 6Carcinoma, Ovarian Epithelial 6Breast Neoplasms 6Thymoma 5Salivary Gland Neoplasms 5Fallopian Tube Neoplasms 5Carcinoma, Hepatocellular 5Astrocytoma 5Urinary Bladder Neoplasms 4Osteosarcoma 4Oligodendroglioma 4Neuroblastoma 4Neoplasm Metastasis 4

Interventions

sacituzumab govitecan 1berzosertib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
NIH × HRD Cancer × Other solid neoplasm × Clear all
NCT04826341 2026-05-29

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

National Institutes of Health Clinical Center (CC)

Phase 1/2 Active not recruiting
35 enrolled
Other solid neoplasmThoracic

HRD Cancer

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