Announcements Trials
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Phase

Phase 1 2

Status

Completed 5Terminated 2Active not recruiting 2Unknown 1Recruiting 1No longer available 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 15CNS 13Sarcoma 12Genitourinary 11Lymphoid 9Myeloid 8Dermatologic 3Other solid neoplasm 2Endocrine 2Head & Neck 1

Conditions

Advanced Solid Tumor 30Mesothelioma 20Solid Tumor 18Mesothelioma, Malignant 18Advanced Solid Tumors 18Solid Tumors 16Solid Tumor, Adult 11Melanoma 10Carcinoma, Non-Small-Cell Lung 10Ovarian Neoplasms 8Colorectal Neoplasms 8Retinoblastoma 7Carcinoma, Renal Cell 7Uterine Cervical Neoplasms 6Squamous Cell Carcinoma of Head and Neck 6Lung Neoplasms 6Cholangiocarcinoma 6Advanced Malignant Solid Neoplasm 6Triple Negative Breast Neoplasms 5Sarcoma 5Stomach Neoplasms 4Pancreatic Neoplasms 4Malignant Solid Neoplasm 4Esophageal Neoplasms 4Advanced or Metastatic Solid Tumors 4Small Cell Lung Carcinoma 3Neoplasms 3Malignant Solid Tumor 3Locally Advanced or Metastatic Solid Tumors 3Hematopoietic and Lymphatic System Neoplasm 3

Interventions

pembrolizumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Active not recruiting × Hepatoblastoma × Other solid neoplasm × Clear all
NCT04483778 2026-04-28

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

Phase 1 Active not recruiting
68 enrolled
CNSDermatologicGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT03618381 2025-11-20

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

Phase 1 Active not recruiting
44 enrolled
CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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