Announcements Trials
Browse Landscape

Phase

Phase 1 3

Status

Terminated 2Completed 1

Sponsor Class

NIH 3

Study Type

Interventional 3

Sponsor

Cancer Type

Thoracic 24Other solid neoplasm 3Sarcoma 2Head & Neck 2Gastrointestinal 2Dermatologic 1

Conditions

Unspecified Adult Solid Tumor, Protocol Specific 4Lung Neoplasms 3Thymoma 2Mesothelioma, Malignant 2Esophageal Neoplasms 2Solid Tumor, Adult 1Solid Tumor 1Small Cell Lung Carcinoma 1Sarcoma 1Mesothelioma 1Carcinoma, Non-Small-Cell Lung 1

Interventions

Cyclophosphamide 6pembrolizumab 5Cisplatin 4sargramostim 3Pemetrexed 3Decitabine 3Celecoxib 3fludarabine 2belinostat 2SS1(dsFv)PE38 2Quality of Life 2Plicamycin 2Nivolumab 2Ipilimumab 2FANG vaccine 2Drug Therapy 2perflutren 1olaparib 1niraparib 1iodixanol 1incomplete Freund's adjuvant 1fludarabine phosphate 1dostarlimab 1anetumab ravtansine 1aldesleukin 1alanosine 1Vorinostat 1Valacyclovir 1UV1 vaccine 1Tumor Burden 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Lung Neoplasms × Celecoxib × Other solid neoplasm × Clear all
NCT01143545 2020-03-03

Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomas

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
10 enrolled
GastrointestinalOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Esophageal Neoplasms, Lung Neoplasms, Sarcoma, Thymoma

NCT01258868 2019-12-03

Tumor Cell Vaccines With ISCOMATRIX Adjuvant and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers and Malignant Pleural Mesotheliomas

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
44 enrolled
GastrointestinalOther solid neoplasmThoracic

Esophageal Neoplasms, Lung Neoplasms, Mesothelioma, Thymoma

NCT00037817 2019-09-30

Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion With or Without Concurrent Celecoxib in Subjects With Pulmonary and Pleural Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
34 enrolled
Other solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

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