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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other solid neoplasm 1Gastrointestinal 1

Conditions

Advanced Solid Tumor 12Solid Tumor 6Advanced Solid Tumors 5Sarcoma 3Uterine Cervical Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Solid Tumors 2Small Cell Lung Carcinoma 2Mesothelioma 2Melanoma 2Carcinoma, Renal Cell 2Anus Neoplasms 2Advanced Solid Tumour 2Uveal Melanoma 1Triple Negative Breast Neoplasms 1Thyroid Neoplasms 1Testicular Germ Cell Tumor 1Stomach Neoplasms 1Solid Tumor, Adult 1Neoplasms, Unknown Primary 1Metastatic Solid Tumors 1Mesothelioma, Malignant 1Malignant Solid Tumors 1MSI-H/dMMR Solid Tumors 1MSI-H Colorectal Cancer 1Locally Advanced or Metastatic Solid Tumors for Phase 1, Dose Escalation and Phase 2 Safety Lead-in 1Locally Advanced or Metastatic Solid Tumors 1Locally Advanced and Metastatic Solid Tumors 1Colorectal Neoplasms 1Cholangiocarcinoma 1

Interventions

Injections 2Infusions, Intravenous 2tislelizumab 1sacituzumab govitecan 1bintrafusp alfa protein, human 1avelumab 1Tomography, X-Ray Computed 1Platinum 1Nivolumab 1Ipilimumab 1Iodine-125 1Gemcitabine 1FANG vaccine 1Electrocardiography 1Echocardiography 1DOXO-EMCH 1Cetuximab 1Cell- and Tissue-Based Therapy 1Antibodies, Bispecific 1(2,4-dihydroxy-5-isopropylphenyl)-(5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl)methanone 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Metastatic Solid Tumors × tislelizumab × Other solid neoplasm × Clear all
NCT06585488 2026-06-03

A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification

BeOne Medicines

Phase 1 Terminated
47 enrolled
GastrointestinalOther solid neoplasmThoracic

Metastatic Solid Tumors

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